ID   U518_DROYA              Reviewed;        1050 AA.
AC   B4NXB9;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=FHIP family protein GE18198;
GN   ORFNames=GE18198;
OS   Drosophila yakuba (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tai18E2 / Tucson 14021-0261.01;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the FHIP family. {ECO:0000305}.
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DR   EMBL; CM000157; EDW87476.1; -; Genomic_DNA.
DR   RefSeq; XP_002087764.1; XM_002087728.2.
DR   RefSeq; XP_015053442.1; XM_015197956.1.
DR   RefSeq; XP_015053443.1; XM_015197957.1.
DR   AlphaFoldDB; B4NXB9; -.
DR   STRING; 7245.FBpp0263208; -.
DR   EnsemblMetazoa; FBtr0264716; FBpp0263208; FBgn0235629.
DR   EnsemblMetazoa; FBtr0402390; FBpp0361243; FBgn0235629.
DR   EnsemblMetazoa; FBtr0402604; FBpp0361443; FBgn0235629.
DR   GeneID; 6526656; -.
DR   KEGG; dya:Dyak_GE18198; -.
DR   eggNOG; KOG3695; Eukaryota.
DR   HOGENOM; CLU_007807_0_0_1; -.
DR   OMA; CLDWDSG; -.
DR   OrthoDB; 141539at2759; -.
DR   PhylomeDB; B4NXB9; -.
DR   Proteomes; UP000002282; Chromosome 2L.
DR   InterPro; IPR019384; FHIP.
DR   InterPro; IPR045669; FHIP_C.
DR   InterPro; IPR045668; FHIP_KELAA_motif.
DR   PANTHER; PTHR21705; PTHR21705; 1.
DR   Pfam; PF19314; DUF5917; 1.
DR   Pfam; PF19311; KELAA; 1.
DR   Pfam; PF10257; RAI16-like; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein.
FT   CHAIN           1..1050
FT                   /note="FHIP family protein GE18198"
FT                   /id="PRO_0000379015"
FT   REGION          800..827
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          865..888
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          911..954
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          968..995
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        804..827
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         498
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         805
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   1050 AA;  114953 MW;  45DA32FF0E0FD702 CRC64;
     MWLRQSSGGG VASAGHGGPL RQRPIDAATD CDPRACYDSF CKHWQQAFEI IQHSAPPSHD
     DVLGVVSHLD YMVTLLLVEL HHCNKVSLPA AEASGPPAAP CLEFLLSENL LDKLYEWACT
     TGRYANAVRL EQLKLYELLV SHSRHQLLCH EPFLRPLLKI LASSQGEIFP PDLEKRLVIL
     LNQLCVVLMQ NVHLLDLFFF SAQTQVQEQI LNGNVAPPKS GTTTNFIIFS LLIPYVHREG
     SLGHQARDAL LLCMALSQKN SNIGTYIAQY SSICPLLVTG LGGLYSRLPN SIEISSIDWH
     RITPDDVTEI PELTLFMNAL EFCNAVVQVA HEMIKQQLLD FMYQGFIVPV LGPAILQTLK
     GKHFQTNIDS QISAMSYLDL ILRSITEPGL LRAFVRFLLD TEKFDGERIL DALVERLNSP
     DANLCMVTMA LFDTLLGLHC EDLMLELLLK FMLPGKHVPI SHRHKINKID PYLNSSEFFL
     DLSPDVMKRA RDLARPKSVH EPVVSDLTPL PSLPSPVMSK TIGANWNYYG VHTGDSLYAN
     IQAYLFEAHW RIAQCQRDCL KWANSYRYQK WPRHGQGRVH AHALELARQF FSEFGGGPIA
     ANETSEKQLD SLQSIGESSG YESFKWRPAD EESEATDTTL ATTASEADLD HNSSSLSSVL
     GASSKREAWR TSNNNRNELI LTDLEFSEDL FAQGTVSLGP FLNAIWGKLQ TFTSNSLYVN
     LHLTGLITRL AWYPLPLIHS LLLRSDIAIT SDTPSFHQVL RILKQQIDAE LPVTEDSLEI
     IDVARSSLID REFRLANARK GNEGSPMHHS QQQQMATNSG QQQGQLRSAY ATLSAATPVQ
     ATPTSAYDPF KRSDNKRRSI SKSITSMFSR KSASNTSTTP PNGSSASSGL SQIYAFFTGA
     ASNLVGTNAS TDGRGMSHAQ TSAGTCETSL STQPQAGAPR TGAIATSATA SGSNSSIAGS
     TLTLSAQSNT TTHSASTLHG LDGGPSTGGF NSEPASLDSV ASMGIIASTS GTERSRDLAL
     CAVLMDEWLK ELAAIAQEQS VVLVTEQGSL