C75AK_ARATH
ID C75AK_ARATH Reviewed; 510 AA.
AC Q9LJY7;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Cytochrome P450 705A20;
DE EC=1.14.-.-;
GN Name=CYP705A20; OrderedLocusNames=At3g20110; ORFNames=MAL21.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR EMBL; AP000383; BAB01871.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE76334.1; -; Genomic_DNA.
DR EMBL; BT006102; AAP04087.1; -; mRNA.
DR EMBL; AK118830; BAC43420.1; -; mRNA.
DR RefSeq; NP_188646.1; NM_112902.3.
DR AlphaFoldDB; Q9LJY7; -.
DR SMR; Q9LJY7; -.
DR BioGRID; 6886; 7.
DR IntAct; Q9LJY7; 7.
DR STRING; 3702.AT3G20110.1; -.
DR iPTMnet; Q9LJY7; -.
DR PaxDb; Q9LJY7; -.
DR PRIDE; Q9LJY7; -.
DR ProteomicsDB; 239212; -.
DR EnsemblPlants; AT3G20110.1; AT3G20110.1; AT3G20110.
DR GeneID; 821554; -.
DR Gramene; AT3G20110.1; AT3G20110.1; AT3G20110.
DR KEGG; ath:AT3G20110; -.
DR Araport; AT3G20110; -.
DR TAIR; locus:2087585; AT3G20110.
DR eggNOG; KOG0156; Eukaryota.
DR HOGENOM; CLU_001570_4_0_1; -.
DR InParanoid; Q9LJY7; -.
DR OMA; PVARTIK; -.
DR OrthoDB; 702827at2759; -.
DR PhylomeDB; Q9LJY7; -.
DR BioCyc; ARA:AT3G20110-MON; -.
DR PRO; PR:Q9LJY7; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LJY7; baseline and differential.
DR Genevisible; Q9LJY7; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IBA:GO_Central.
DR Gene3D; 1.10.630.10; -; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; SSF48264; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 2: Evidence at transcript level;
KW Heme; Iron; Membrane; Metal-binding; Monooxygenase; Oxidoreductase;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..510
FT /note="Cytochrome P450 705A20"
FT /id="PRO_0000326467"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 510 AA; 58049 MW; D8DC144217E2918E CRC64;
MLTVDSQHCF SFILLCFFSL LCYSLLFKKL KDSHVGRDLL QSPPSLPIIG HLHHLLSSLA
HKSLQQLSSK YGPLLHLSIF NFPVVLVSSA SVAYEIFKAH DLNISSRDNP PINESLLVGS
SVFVGAPYGD YWKFMKKLLV TKLLGPQALE RSRSIRADEL ERFYRSLLDK AMKKESVEIG
KEATKLSINS ICRMSMGRSF SEESGEAERV RGLVTELDGL TKKVLLVNIL RWPLEKLRIS
LFKKEIMYVS NSFDELLERI IVEREKKPNE HQGTYLMDVL LEAYEDEKAE HKITRNHIKS
LFVELLLGGT DTSAQTIQWT MAELINNRNV LKRLREEIDS VVGETRLIQE KDLPKLPYLQ
SVVKEGLRLH PPLPLMVRTF QRSCEMKGFY IAEKTTLVVN AYAVMRDPTT WEDPDEFKPE
RFLRQEEERR ALKHIAFGSG RRGCPGSNLA TIFIGTAIGT MVQCFDLSIK GDKVKMDEVG
GLNLTMAHPL ECILVPRTQP FISNQQIPSL
