U518_MONBE
ID U518_MONBE Reviewed; 880 AA.
AC A9UYK7;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 1.
DT 25-MAY-2022, entry version 29.
DE RecName: Full=FHIP family protein 36947;
GN ORFNames=36947;
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154;
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
CC -!- SIMILARITY: Belongs to the FHIP family. {ECO:0000305}.
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DR EMBL; CH991550; EDQ89479.1; -; Genomic_DNA.
DR RefSeq; XP_001745508.1; XM_001745456.1.
DR AlphaFoldDB; A9UYK7; -.
DR STRING; 81824.XP_001745508.1; -.
DR EnsemblProtists; EDQ89479; EDQ89479; MONBRDRAFT_36947.
DR GeneID; 5890961; -.
DR KEGG; mbr:MONBRDRAFT_36947; -.
DR eggNOG; KOG3695; Eukaryota.
DR InParanoid; A9UYK7; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR InterPro; IPR019384; FHIP.
DR InterPro; IPR045669; FHIP_C.
DR InterPro; IPR045668; FHIP_KELAA_motif.
DR PANTHER; PTHR21705; PTHR21705; 1.
DR Pfam; PF19314; DUF5917; 1.
DR Pfam; PF19311; KELAA; 1.
DR Pfam; PF10257; RAI16-like; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..880
FT /note="FHIP family protein 36947"
FT /id="PRO_0000379017"
FT REGION 437..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 677..805
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 746..762
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..805
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 880 AA; 94995 MW; 562284709676E7E9 CRC64;
MAGLMSRLRA ARGGDGPSGA QLHSEAGRAA LFDTALSKLY KTIDQMQTKR VHLFNPIKTA
EEQLQQIYLV LEAEEASIHD GMTGACLQYL LTSQRLHNIA KGLLGDQPLG ARLVWLSFIL
QVLSHLKHPL LIHAEVLEAL NSTIKVLRRD QRRLALAEAN IYMQLLLRLT EYLERNPSCL
PLFLEEKPQP AFPLLAALMP FVQHHTDEGK LARKAVVTCC QLANHSQQLE QFLLRHEIFA
AEVAGALAGA YSNLPMSLPA RSRKALKAWA YGAKAFSHRV PRAAHYFNAL TFCGQVVRAV
PSSVRGLILD QVYHGFMLSV LLPSLHHRAP EEAVAAMNYL RISLSRTRNT PLQGAFLRLL
LASQFEGCWT LDRLVERLET LGEQSLTALS LFQALIRLHN EDVLLRLCLR FVHRPLARAA
AAASRPPYPG TLMPADSGCN SEPESDIGTG TSTNTGAANH TGAGTDTSTS VHADKSNRVQ
LQGGTHPNGS SDVSAFALHN ALEMRAGRKL LQLVPAQTAI SPSERTFEGY LHAASQGVDA
ACAACATWRL SYLQLRPHQW LGKEDLDIDA ATVNDNASAV SRCESEGLFL ATLSRLTRRM
LEHNLATNLL LSSIVSMLAS LPVPALRNYL LDLNSPSIEG ISFVEQLHAL REDCLRLLAE
DEGLEANLHA YRAGAEGYSR PKHRVKAPST TAPASPARGP LATFHSSRRS RDRAASIVAL
PPHSAANEPG GVSTSAPTPA SRASDADGAS RRDARPEEPT IDDEAATTSN GGFDDGTSEQ
DSDSVCSSYS GSSSHRASAV SASHPSTRLT AAALATLDQE RPPLPSPALG ATTDTAPSVS
AVGDEIKDSK RRALKVLIVQ EFVKELAACA MEQSLLAVAM