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U585_DROME
ID   U585_DROME              Reviewed;         222 AA.
AC   Q9VLF6; Q8MRW6;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 2.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=UPF0585 protein CG18661;
GN   ORFNames=CG18661;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Berkeley; TISSUE=Embryo;
RX   PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA   Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA   Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA   Celniker S.E.;
RT   "A Drosophila full-length cDNA resource.";
RL   Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC   -!- SIMILARITY: Belongs to the UPF0585 family. {ECO:0000305}.
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DR   EMBL; AE014134; AAF52737.2; -; Genomic_DNA.
DR   EMBL; AY119228; AAM51088.1; -; mRNA.
DR   RefSeq; NP_652562.2; NM_144305.5.
DR   AlphaFoldDB; Q9VLF6; -.
DR   SMR; Q9VLF6; -.
DR   STRING; 7227.FBpp0079364; -.
DR   PaxDb; Q9VLF6; -.
DR   EnsemblMetazoa; FBtr0079763; FBpp0079364; FBgn0040964.
DR   GeneID; 50438; -.
DR   KEGG; dme:Dmel_CG18661; -.
DR   UCSC; CG18661-RA; d. melanogaster.
DR   FlyBase; FBgn0040964; CG18661.
DR   VEuPathDB; VectorBase:FBgn0040964; -.
DR   eggNOG; ENOG502QVX9; Eukaryota.
DR   GeneTree; ENSGT00390000010750; -.
DR   HOGENOM; CLU_067698_0_0_1; -.
DR   InParanoid; Q9VLF6; -.
DR   OrthoDB; 1359763at2759; -.
DR   PhylomeDB; Q9VLF6; -.
DR   BioGRID-ORCS; 50438; 0 hits in 1 CRISPR screen.
DR   GenomeRNAi; 50438; -.
DR   PRO; PR:Q9VLF6; -.
DR   Proteomes; UP000000803; Chromosome 2L.
DR   Bgee; FBgn0040964; Expressed in antenna and 19 other tissues.
DR   ExpressionAtlas; Q9VLF6; baseline and differential.
DR   Genevisible; Q9VLF6; DM.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR010342; DUF938.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR20974; PTHR20974; 1.
DR   Pfam; PF06080; DUF938; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..222
FT                   /note="UPF0585 protein CG18661"
FT                   /id="PRO_0000337121"
FT   CONFLICT        43..44
FT                   /note="TE -> SQ (in Ref. 3; AAM51088)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        135
FT                   /note="S -> A (in Ref. 3; AAM51088)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        209
FT                   /note="K -> E (in Ref. 3; AAM51088)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   222 AA;  24887 MW;  1C93198A41E882A0 CRC64;
     MSLTKRLLHI HPRCSFSKRS HPSADRNSQP ISEALLSQVD KTTENLQLLE IASGSGQHAG
     FLAPLLPNIT FQPTEYERNQ FGSIAAYAGD CPTRNIRPPF HVDITRDPGD WEAPPAPASY
     DYMFNSNMMH ISPWSCSIGL FRAAGQLLKK GGRMFTYGPY AQDGILVPQS NVDFDRSLRQ
     RDASWGVRDI KDLKVLAAEN GLQLEKLVKM PSNNKFLTWL KL
 
 
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