U587_DROPS
ID U587_DROPS Reviewed; 163 AA.
AC Q290L7;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 04-APR-2006, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=UPF0587 protein GA18326;
GN ORFNames=GA18326;
OS Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=46245;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MV2-25 / Tucson 14011-0121.94;
RX PubMed=15632085; DOI=10.1101/gr.3059305;
RA Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA Weinstock G.M., Gibbs R.A.;
RT "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT gene, and cis-element evolution.";
RL Genome Res. 15:1-18(2005).
CC -!- DOMAIN: Requires a bound zinc ion for normal folding and solubility.
CC {ECO:0000250|UniProtKB:Q9NWV4}.
CC -!- SIMILARITY: Belongs to the UPF0587 family. {ECO:0000305}.
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DR EMBL; CM000071; EAL25345.1; -; Genomic_DNA.
DR RefSeq; XP_001360770.1; XM_001360733.3.
DR AlphaFoldDB; Q290L7; -.
DR SMR; Q290L7; -.
DR STRING; 7237.FBpp0276662; -.
DR EnsemblMetazoa; FBtr0278224; FBpp0276662; FBgn0078331.
DR GeneID; 4804166; -.
DR KEGG; dpo:Dpse_GA18326; -.
DR eggNOG; KOG1296; Eukaryota.
DR HOGENOM; CLU_114688_1_0_1; -.
DR InParanoid; Q290L7; -.
DR OMA; FFMKCKM; -.
DR PhylomeDB; Q290L7; -.
DR Proteomes; UP000001819; Chromosome 3.
DR Bgee; FBgn0078331; Expressed in female reproductive system and 2 other tissues.
DR GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR InterPro; IPR008584; CXXC_Zn-binding_euk.
DR PANTHER; PTHR12857; PTHR12857; 1.
DR Pfam; PF05907; DUF866; 1.
PE 3: Inferred from homology;
KW Metal-binding; Reference proteome; Zinc.
FT CHAIN 1..163
FT /note="UPF0587 protein GA18326"
FT /id="PRO_0000337876"
FT BINDING 33
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT BINDING 36
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT BINDING 68
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT BINDING 71
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:Q9NWV4"
SQ SEQUENCE 163 AA; 18721 MW; 15F2E100E90415E7 CRC64;
MVRVGLQISA TLENIDKLET SHPDYPFFVK LTCSNCGEQS DKWHDITESE RVQQDTRNTA
GFNFFMKCKM CSRENSIDIV EKSNVPYTAD DSGKLKTIVI FDCRGLEPVD FSPRSGWKVF
SSENGQSFED VDLSEDDWVE YDQKNNNSVG VYEFVSKFIK LKK