ID   C76A2_SOLME             Reviewed;         505 AA.
AC   P37122;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Cytochrome P450 76A2;
DE            EC=1.14.-.-;
DE   AltName: Full=CYPLXXVIA2;
DE   AltName: Full=Cytochrome P-450EG7;
GN   Name=CYP76A2; Synonyms=CYPEG7;
OS   Solanum melongena (Eggplant) (Aubergine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4111;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Sinsadoharanasu; TISSUE=Hypocotyl;
RX   PubMed=8218411; DOI=10.1016/0167-4781(93)90058-l;
RA   Toguri T., Kobayashi O., Umemoto N.;
RT   "The cloning of eggplant seedling cDNAs encoding proteins from a novel
RT   cytochrome P-450 family (CYP76).";
RL   Biochim. Biophys. Acta 1216:165-169(1993).
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR   EMBL; X71657; CAA50648.1; -; mRNA.
DR   PIR; S38534; S38534.
DR   AlphaFoldDB; P37122; -.
DR   SMR; P37122; -.
DR   KEGG; ag:CAA50648; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   Gene3D; 1.10.630.10; -; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; SSF48264; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   2: Evidence at transcript level;
KW   Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase.
FT   CHAIN           1..505
FT                   /note="Cytochrome P450 76A2"
FT                   /id="PRO_0000052139"
FT   BINDING         448
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   505 AA;  57807 MW;  CF4AAA8B8DD4A604 CRC64;
     MEWEWSYVFF SAIIILPAFI LFFSQKNTTK SSYKFPPGPP GLPIFGNMFE LGTEPYKKMA
     VLRQKYGPVL WLKLGSTYTM VVQTAQASEE LFKNHDISFA NRVIPDVNQA HSYYQGSLAI
     APYGPFWRFQ RRICTIEMFV HKKISETEPV RRKCVDNMLK WIEKEANSAE KGSGIEVTRF
     VFLASFNMLG NLILSKDLAD LESEEASEFF IAMKRINEWS GIANVSDIFP FLKKFDLQSL
     RKKMARDMGK AVEIMSMFLK EREEERKKGT EKGKDFLDVL LEFQGTGKDE PAKLSEHEIK
     IFVLEMFLAG TETTSSSVEW ALTELLRHPE AMAKVKTEIS QAIEPNRKFE DSDIENLPYM
     QAVLKESLRL HPPLPFLIPR ETIQDTKFMG YDVPKDTQVL VNAWAIGRDP ECWDDPMSFK
     PERFLGSKID VKGQHYGLIP FGAGRRMCVG LPLGHRMMHF ALGSLLREFE WELPDGVSPK
     SINMDGSMGV TARKRDSLKV IPKKA