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U605_DROME
ID   U605_DROME              Reviewed;         323 AA.
AC   Q7JRP4;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=UPF0605 protein CG18335;
GN   ORFNames=CG18335;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Berkeley; TISSUE=Testis;
RX   PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA   Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA   Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA   Celniker S.E.;
RT   "A Drosophila full-length cDNA resource.";
RL   Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC   -!- SIMILARITY: Belongs to the UPF0605 family. {ECO:0000305}.
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DR   EMBL; AE013599; AAF58679.2; -; Genomic_DNA.
DR   EMBL; BT001366; AAN71121.1; -; mRNA.
DR   EMBL; BT012323; AAS77448.1; -; mRNA.
DR   RefSeq; NP_610666.1; NM_136822.4.
DR   AlphaFoldDB; Q7JRP4; -.
DR   STRING; 7227.FBpp0087273; -.
DR   PaxDb; Q7JRP4; -.
DR   PRIDE; Q7JRP4; -.
DR   DNASU; 36202; -.
DR   EnsemblMetazoa; FBtr0088177; FBpp0087273; FBgn0033610.
DR   GeneID; 36202; -.
DR   KEGG; dme:Dmel_CG18335; -.
DR   UCSC; CG18335-RA; d. melanogaster.
DR   FlyBase; FBgn0033610; CG18335.
DR   VEuPathDB; VectorBase:FBgn0033610; -.
DR   eggNOG; ENOG502RTSD; Eukaryota.
DR   GeneTree; ENSGT00940000166013; -.
DR   HOGENOM; CLU_065650_1_0_1; -.
DR   InParanoid; Q7JRP4; -.
DR   OMA; CCGQDLT; -.
DR   OrthoDB; 851402at2759; -.
DR   PhylomeDB; Q7JRP4; -.
DR   BioGRID-ORCS; 36202; 0 hits in 3 CRISPR screens.
DR   ChiTaRS; CG18335; fly.
DR   GenomeRNAi; 36202; -.
DR   PRO; PR:Q7JRP4; -.
DR   Proteomes; UP000000803; Chromosome 2R.
DR   Bgee; FBgn0033610; Expressed in testis and 6 other tissues.
DR   Genevisible; Q7JRP4; DM.
DR   InterPro; IPR018902; FAM166/UPF0605.
DR   Pfam; PF10629; DUF2475; 2.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..323
FT                   /note="UPF0605 protein CG18335"
FT                   /id="PRO_0000342388"
SQ   SEQUENCE   323 AA;  36822 MW;  517FD502476E7D04 CRC64;
     MDHAITPEPH LVPGYTGHCA QNRDRVGRTY GRQTHKLLID PCIYHAPELI VAPIHAKRGL
     KDYPTEQELK ILRTREGLVD SVYRHPILPG YAGFVPNKVS QIGKRYVAAA SAGVARHETL
     MELYRCENRT LRHRDLLESG NGLFDRKINE RLLPQTYYRS PLILVTGVSK GIKDETCPPK
     TEKLCYSKFT SPHFLEDEDA DKFIINGYSG HIPMSVTRFG ESNKVLTNRA LCSFSDYMYK
     RKRDTWCCGQ DLSRPSITCP PVGHFVVYHE DSGMVPNYAG HVPGETYKFG RTYAKTTYDA
     KRWLEVHKNL TVLPEVANLD YAY
 
 
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