U72B3_ARATH
ID U72B3_ARATH Reviewed; 481 AA.
AC Q9LNI1; Q681W3;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=UDP-glycosyltransferase 72B3;
DE EC=2.4.1.-;
GN Name=UGT72B3; OrderedLocusNames=At1g01420; ORFNames=F6F3.22;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista-Mercan V.R., Kim C.J., Chen H., Wu S.Y., De Los Reyes C.,
RA Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 14-481.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=11042215; DOI=10.1074/jbc.m007447200;
RA Li Y., Baldauf S., Lim E.K., Bowles D.J.;
RT "Phylogenetic analysis of the UDP-glycosyltransferase multigene family of
RT Arabidopsis thaliana.";
RL J. Biol. Chem. 276:4338-4343(2001).
RN [6]
RP FUNCTION.
RX PubMed=15352060; DOI=10.1002/bit.20154;
RA Lim E.K., Ashford D.A., Hou B., Jackson R.G., Bowles D.J.;
RT "Arabidopsis glycosyltransferases as biocatalysts in fermentation for
RT regioselective synthesis of diverse quercetin glucosides.";
RL Biotechnol. Bioeng. 87:623-631(2004).
CC -!- FUNCTION: Possesses low quercetin 3-O-glucosyltransferase activity in
CC vitro. {ECO:0000269|PubMed:15352060}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000305}.
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DR EMBL; AC023628; AAF97321.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27284.1; -; Genomic_DNA.
DR EMBL; BT030469; ABP88123.1; -; mRNA.
DR EMBL; AK175504; BAD43267.1; -; mRNA.
DR PIR; G86144; G86144.
DR RefSeq; NP_171649.1; NM_100024.2.
DR AlphaFoldDB; Q9LNI1; -.
DR SMR; Q9LNI1; -.
DR STRING; 3702.AT1G01420.1; -.
DR CAZy; GT1; Glycosyltransferase Family 1.
DR PaxDb; Q9LNI1; -.
DR PRIDE; Q9LNI1; -.
DR ProteomicsDB; 228522; -.
DR DNASU; 837503; -.
DR EnsemblPlants; AT1G01420.1; AT1G01420.1; AT1G01420.
DR GeneID; 837503; -.
DR Gramene; AT1G01420.1; AT1G01420.1; AT1G01420.
DR KEGG; ath:AT1G01420; -.
DR Araport; AT1G01420; -.
DR TAIR; locus:2035332; AT1G01420.
DR eggNOG; KOG1192; Eukaryota.
DR HOGENOM; CLU_001724_3_0_1; -.
DR InParanoid; Q9LNI1; -.
DR PhylomeDB; Q9LNI1; -.
DR PRO; PR:Q9LNI1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LNI1; baseline and differential.
DR Genevisible; Q9LNI1; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
DR GO; GO:0080043; F:quercetin 3-O-glucosyltransferase activity; IDA:TAIR.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR Pfam; PF00201; UDPGT; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 2: Evidence at transcript level;
KW Glycosyltransferase; Reference proteome; Transferase.
FT CHAIN 1..481
FT /note="UDP-glycosyltransferase 72B3"
FT /id="PRO_0000409070"
FT BINDING 277
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 347..349
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 364..372
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 386..389
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
SQ SEQUENCE 481 AA; 52784 MW; CA775646EF05364B CRC64;
MADGNTPHVA IIPSPGIGHL IPLVELAKRL LDNHGFTVTF IIPGDSPPSK AQRSVLNSLP
SSIASVFLPP ADLSDVPSTA RIETRISLTV TRSNPALREL FGSLSAEKRL PAVLVVDLFG
TDAFDVAAEF HVSPYIFYAS NANVLTFLLH LPKLDETVSC EFRELTEPVI IPGCVPITGK
DFVDPCQDRK DESYKWLLHN VKRFKEAEGI LVNSFVDLEP NTIKIVQEPA PDKPPVYLIG
PLVNSGSHDA DVNDEYKCLN WLDNQPFGSV LYVSFGSGGT LTFEQFIELA LGLAESGKRF
LWVIRSPSGI ASSSYFNPQS RNDPFSFLPQ GFLDRTKEKG LVVGSWAPQA QILTHTSIGG
FLTHCGWNSS LESIVNGVPL IAWPLYAEQK MNALLLVDVG AALRARLGED GVVGREEVAR
VVKGLIEGEE GNAVRKKMKE LKEGSVRVLR DDGFSTKSLN EVSLKWKAHQ RKIDQEQESF
L
