U74E1_ARATH
ID U74E1_ARATH Reviewed; 453 AA.
AC P0C7P7; Q9SYK8;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-2008, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=UDP-glycosyltransferase 74E1;
DE EC=2.4.1.-;
GN Name=UGT74E1; OrderedLocusNames=At1g05675; ORFNames=F3F20.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=11042215; DOI=10.1074/jbc.m007447200;
RA Li Y., Baldauf S., Lim E.K., Bowles D.J.;
RT "Phylogenetic analysis of the UDP-glycosyltransferase multigene family of
RT Arabidopsis thaliana.";
RL J. Biol. Chem. 276:4338-4343(2001).
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD30619.1; Type=Erroneous gene model prediction; Note=The predicted gene At1g05670 has been split into 2 genes: At1g05670 and At1g05675.; Evidence={ECO:0000305};
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DR EMBL; AC007153; AAD30619.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE27875.1; -; Genomic_DNA.
DR PIR; H86190; H86190.
DR RefSeq; NP_001184915.1; NM_001197986.1.
DR AlphaFoldDB; P0C7P7; -.
DR SMR; P0C7P7; -.
DR IntAct; P0C7P7; 1.
DR STRING; 3702.AT1G05675.1; -.
DR CAZy; GT1; Glycosyltransferase Family 1.
DR PaxDb; P0C7P7; -.
DR PRIDE; P0C7P7; -.
DR ProteomicsDB; 228676; -.
DR EnsemblPlants; AT1G05675.1; AT1G05675.1; AT1G05675.
DR GeneID; 10723139; -.
DR Gramene; AT1G05675.1; AT1G05675.1; AT1G05675.
DR KEGG; ath:AT1G05675; -.
DR Araport; AT1G05675; -.
DR TAIR; locus:6530298131; AT1G05675.
DR eggNOG; KOG1192; Eukaryota.
DR HOGENOM; CLU_001724_0_1_1; -.
DR OMA; INHEDST; -.
DR OrthoDB; 508327at2759; -.
DR PhylomeDB; P0C7P7; -.
DR PRO; PR:P0C7P7; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; P0C7P7; baseline and differential.
DR GO; GO:0080043; F:quercetin 3-O-glucosyltransferase activity; IBA:GO_Central.
DR GO; GO:0080044; F:quercetin 7-O-glucosyltransferase activity; IBA:GO_Central.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR Pfam; PF00201; UDPGT; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase; Reference proteome; Transferase.
FT CHAIN 1..453
FT /note="UDP-glycosyltransferase 74E1"
FT /id="PRO_0000342602"
FT BINDING 279
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 332..334
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 349..357
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 371..374
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
SQ SEQUENCE 453 AA; 51172 MW; 634B69784C1F17E2 CRC64;
MREGSHVIVL PFPAQGHITP MSQFCKRLAS KSLKITLVLV SDKPSPPYKT EHDTITVVPI
SNGFQEGQER SEDLDEYMER VESSIKNRLP KLIEDMKLSG NPPRALVYDS TMPWLLDVAH
SYGLSGAVFF TQPWLVSAIY YHVFKGSFSV PSTKYGHSTL ASFPSLPILN ANDLPSFLCE
SSSYPYILRT VIDQLSNIDR VDIVLCNTFD KLEEKLLKWI KSVWPVLNIG PTVPSMYLDK
RLAEDKNYGF SLFGAKIAEC MEWLNSKQPS SVVYVSFGSL VVLKKDQLIE LAAGLKQSGH
FFLWVVRETE RRKLPENYIE EIGEKGLTVS WSPQLEVLTH KSIGCFVTHC GWNSTLEGLS
LGVPMIGMPH WADQPTNAKF MEDVWKVGVR VKADSDGFVR REEFVRRVEE VMEAEQGKEI
RKNAEKWKVL AQEAVSEGGS SDKNINEFVS MFC
