U76D1_ARATH
ID U76D1_ARATH Reviewed; 452 AA.
AC O48715;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=UDP-glycosyltransferase 76D1;
DE EC=2.4.1.-;
GN Name=UGT76D1; OrderedLocusNames=At2g26480; ORFNames=T9J22.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 5-452.
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=11042215; DOI=10.1074/jbc.m007447200;
RA Li Y., Baldauf S., Lim E.K., Bowles D.J.;
RT "Phylogenetic analysis of the UDP-glycosyltransferase multigene family of
RT Arabidopsis thaliana.";
RL J. Biol. Chem. 276:4338-4343(2001).
RN [5]
RP FUNCTION.
RX PubMed=15352060; DOI=10.1002/bit.20154;
RA Lim E.K., Ashford D.A., Hou B., Jackson R.G., Bowles D.J.;
RT "Arabidopsis glycosyltransferases as biocatalysts in fermentation for
RT regioselective synthesis of diverse quercetin glucosides.";
RL Biotechnol. Bioeng. 87:623-631(2004).
CC -!- FUNCTION: Possesses low quercetin 7-O-glucosyltransferase activity in
CC vitro. {ECO:0000269|PubMed:15352060}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BX821030; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR EMBL; AC002505; AAC14497.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07843.1; -; Genomic_DNA.
DR EMBL; BX821030; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; T00981; T00981.
DR RefSeq; NP_180216.1; NM_128205.3.
DR AlphaFoldDB; O48715; -.
DR SMR; O48715; -.
DR STRING; 3702.AT2G26480.1; -.
DR CAZy; GT1; Glycosyltransferase Family 1.
DR PaxDb; O48715; -.
DR PRIDE; O48715; -.
DR ProteomicsDB; 243208; -.
DR EnsemblPlants; AT2G26480.1; AT2G26480.1; AT2G26480.
DR GeneID; 817189; -.
DR Gramene; AT2G26480.1; AT2G26480.1; AT2G26480.
DR KEGG; ath:AT2G26480; -.
DR Araport; AT2G26480; -.
DR TAIR; locus:2066261; AT2G26480.
DR eggNOG; KOG1192; Eukaryota.
DR HOGENOM; CLU_001724_0_0_1; -.
DR InParanoid; O48715; -.
DR OMA; TTEGSSH; -.
DR OrthoDB; 508327at2759; -.
DR PhylomeDB; O48715; -.
DR BioCyc; ARA:AT2G26480-MON; -.
DR PRO; PR:O48715; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O48715; baseline and differential.
DR Genevisible; O48715; AT.
DR GO; GO:0080043; F:quercetin 3-O-glucosyltransferase activity; IBA:GO_Central.
DR GO; GO:0080044; F:quercetin 7-O-glucosyltransferase activity; IDA:TAIR.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR InterPro; IPR002213; UDP_glucos_trans.
DR Pfam; PF00201; UDPGT; 1.
PE 2: Evidence at transcript level;
KW Glycosyltransferase; Reference proteome; Transferase.
FT CHAIN 1..452
FT /note="UDP-glycosyltransferase 76D1"
FT /id="PRO_0000409085"
FT BINDING 269
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 329..331
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 346..354
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 368..371
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
SQ SEQUENCE 452 AA; 51170 MW; 11B98ED216BED3BF CRC64;
MAEIRQRRVL MVPAPFQGHL PSMMNLASYL SSQGFSITIV RNEFNFKDIS HNFPGIKFFT
IKDGLSESDV KSLGLLEFVL ELNSVCEPLL KEFLTNHDDV VDFIIYDEFV YFPRRVAEDM
NLPKMVFSPS SAATSISRCV LMENQSNGLL PPQDARSQLE ETVPEFHPFR FKDLPFTAYG
SMERLMILYE NVSNRASSSG IIHNSSDCLE NSFITTAQEK WGVPVYPVGP LHMTNSAMSC
PSLFEEERNC LEWLEKQETS SVIYISMGSL AMTQDIEAVE MAMGFVQSNQ PFLWVIRPGS
INGQESLDFL PEQFNQTVTD GRGFVVKWAP QKEVLRHRAV GGFWNHGGWN SCLESISSGV
PMICRPYSGD QRVNTRLMSH VWQTAYEIEG ELERGAVEMA VRRLIVDQEG QEMRMRATIL
KEEVEASVTT EGSSHNSLNN LVHAIMMQID EQ
