ID   U76E6_ARATH             Reviewed;         449 AA.
AC   Q9SNB0; Q9STE2;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=UDP-glycosyltransferase 76E6;
DE            EC=2.4.1.-;
GN   Name=UGT76E6; OrderedLocusNames=At3g46680; ORFNames=F12A12.200;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130713; DOI=10.1038/35048706;
RA   Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA   Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA   Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA   Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA   Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA   Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA   Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA   Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA   Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA   Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA   Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA   de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA   Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA   Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA   Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA   Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA   Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA   Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA   Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA   Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA   Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA   Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL   Nature 408:820-822(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=11042215; DOI=10.1074/jbc.m007447200;
RA   Li Y., Baldauf S., Lim E.K., Bowles D.J.;
RT   "Phylogenetic analysis of the UDP-glycosyltransferase multigene family of
RT   Arabidopsis thaliana.";
RL   J. Biol. Chem. 276:4338-4343(2001).
CC   -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC       {ECO:0000305}.
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DR   EMBL; AL096859; CAB51197.1; -; Genomic_DNA.
DR   EMBL; AL133314; CAB62338.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE78193.1; -; Genomic_DNA.
DR   EMBL; DQ446740; ABE65996.1; -; mRNA.
DR   PIR; T45605; T45605.
DR   RefSeq; NP_190252.1; NM_114535.1.
DR   AlphaFoldDB; Q9SNB0; -.
DR   SMR; Q9SNB0; -.
DR   CAZy; GT1; Glycosyltransferase Family 1.
DR   PaxDb; Q9SNB0; -.
DR   PRIDE; Q9SNB0; -.
DR   EnsemblPlants; AT3G46680.1; AT3G46680.1; AT3G46680.
DR   GeneID; 823821; -.
DR   Gramene; AT3G46680.1; AT3G46680.1; AT3G46680.
DR   KEGG; ath:AT3G46680; -.
DR   Araport; AT3G46680; -.
DR   TAIR; locus:2075150; AT3G46680.
DR   eggNOG; KOG1192; Eukaryota.
DR   HOGENOM; CLU_001724_0_0_1; -.
DR   InParanoid; Q9SNB0; -.
DR   OMA; IAGSEWI; -.
DR   OrthoDB; 508327at2759; -.
DR   PhylomeDB; Q9SNB0; -.
DR   BioCyc; ARA:AT3G46680-MON; -.
DR   PRO; PR:Q9SNB0; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9SNB0; baseline and differential.
DR   Genevisible; Q9SNB0; AT.
DR   GO; GO:0080043; F:quercetin 3-O-glucosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0080044; F:quercetin 7-O-glucosyltransferase activity; IBA:GO_Central.
DR   CDD; cd03784; GT1_Gtf-like; 1.
DR   InterPro; IPR002213; UDP_glucos_trans.
DR   Pfam; PF00201; UDPGT; 1.
PE   2: Evidence at transcript level;
KW   Glycosyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..449
FT                   /note="UDP-glycosyltransferase 76E6"
FT                   /id="PRO_0000409091"
FT   BINDING         274
FT                   /ligand="UDP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:58885"
FT                   /evidence="ECO:0000250"
FT   BINDING         333..335
FT                   /ligand="UDP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:58885"
FT                   /evidence="ECO:0000250"
FT   BINDING         350..358
FT                   /ligand="UDP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:58885"
FT                   /evidence="ECO:0000250"
FT   BINDING         372..375
FT                   /ligand="UDP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:58885"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   449 AA;  50336 MW;  4CAEB268A51443BB CRC64;
     MEKMEEKKRI VLVPVPAQRH VTPMMQLGTA LNMKGFSITV VEGQFNKVSS SQNFPGFQFV
     TIPDTESLPE SVLERLGPVE FLFEINKTSE ASFKDCIRQS LLQQGNDIAC IIYDEYMYFC
     GAAAKEFNLP SVIFSTQSAT NQVSRCVLRK LSAEKFLVDM EDPEVQETLV ENLHPLRYKD
     LPTSGVGPLD RLFELCREIV NKRTASAVII NTVRCLESSS LKRLQHELGI PVYALGPLHI
     TVSAASSLLE EDRSCVEWLN KQKPRSVVYI SLGSVVQMET KEVLEMARGL FNSNQPFLWV
     IRPGSIAGSE WIESLPEEVI KMVSERGYIV KWAPQIEVLG HPAVGGFWSH CGWNSTLESI
     VEGVPMICRP FHGEQKLNAL CLESIWRIGF QVQGKVERGG VERAVKRLIV DEEGADMRER
     ALVLKENLKA SVRNGGSSYN ALEEIVNLM