ID   U76H1_STERE             Reviewed;         424 AA.
AC   Q6VAB1;
DT   14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=UDP-glycosyltransferase 76H1 {ECO:0000303|PubMed:15610349};
DE            EC=2.4.1.- {ECO:0000305};
GN   Name=UGT76H1 {ECO:0000303|PubMed:15610349};
OS   Stevia rebaudiana (Stevia) (Eupatorium rebaudianum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC   Heliantheae alliance; Eupatorieae; Stevia.
OX   NCBI_TaxID=55670;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Leaf;
RX   PubMed=15610349; DOI=10.1111/j.1365-313x.2004.02275.x;
RA   Richman A., Swanson A., Humphrey T., Chapman R., McGarvey B., Pocs R.,
RA   Brandle J.;
RT   "Functional genomics uncovers three glucosyltransferases involved in the
RT   synthesis of the major sweet glucosides of Stevia rebaudiana.";
RL   Plant J. 41:56-67(2005).
CC   -!- FUNCTION: May glycosylate diterpenes or flavonols in leaves.
CC       {ECO:0000250|UniProtKB:Q6VAA6}.
CC   -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC       {ECO:0000305}.
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DR   EMBL; AY345977; AAR06915.1; -; mRNA.
DR   AlphaFoldDB; Q6VAB1; -.
DR   SMR; Q6VAB1; -.
DR   CAZy; GT1; Glycosyltransferase Family 1.
DR   GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR   CDD; cd03784; GT1_Gtf-like; 1.
DR   InterPro; IPR002213; UDP_glucos_trans.
DR   Pfam; PF00201; UDPGT; 1.
PE   2: Evidence at transcript level;
KW   Transferase.
FT   CHAIN           1..424
FT                   /note="UDP-glycosyltransferase 76H1"
FT                   /id="PRO_0000434466"
FT   BINDING         248
FT                   /ligand="UDP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:58885"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M156"
FT   BINDING         306..307
FT                   /ligand="UDP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:58885"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M156"
FT   BINDING         324..332
FT                   /ligand="UDP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:58885"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M156"
FT   BINDING         346..349
FT                   /ligand="UDP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:58885"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M156"
SQ   SEQUENCE   424 AA;  47277 MW;  F3615E3F85CBA0EF CRC64;
     MLQLATYLHS QGISITIAQY PNFNSPDSSN HPELTFLPLS SGNLSVADIS GGFFKFIQTL
     NHNCKPHFRE YLVQNMSSDD KESIVIIRDN LMFFAGEIAG ELGLPSIILR GSNAVMLTAS
     DIIPQLHQEG RFPPPDSLLQ ETIPELVPFR YKDLPFIGYP IHQTLEFSIT MMTPKSPASA
     ILINTLEFLE QSALTQIRDH YKVPVFTIGP LHKIVTTRST SILEEDTSCI NWLDKQSPKS
     VVYVSLGSLA KLDEKVASEM ACGLAMSNHK FLWVVRPGMV HGFEWVEFLP DSLVGEMKAR
     GLIVKWAPQT TVLAHNAVGG FWSHCGWNST IECLAEGVPM MCQPFFADQL LNARYVSDVW
     KTGFEIVIEK GEIACAIKRV LVDEEGEEMR QRAMEIKEKV KIAINDGGSS YDSFKDLVAF
     ISSL