U7E11_ARATH
ID U7E11_ARATH Reviewed; 451 AA.
AC Q9SNB1; Q8LFF5;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=UDP-glycosyltransferase 76E11;
DE EC=2.4.1.-;
GN Name=UGT76E11; OrderedLocusNames=At3g46670; ORFNames=F12A12.190;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=11042215; DOI=10.1074/jbc.m007447200;
RA Li Y., Baldauf S., Lim E.K., Bowles D.J.;
RT "Phylogenetic analysis of the UDP-glycosyltransferase multigene family of
RT Arabidopsis thaliana.";
RL J. Biol. Chem. 276:4338-4343(2001).
RN [6]
RP FUNCTION.
RX PubMed=15352060; DOI=10.1002/bit.20154;
RA Lim E.K., Ashford D.A., Hou B., Jackson R.G., Bowles D.J.;
RT "Arabidopsis glycosyltransferases as biocatalysts in fermentation for
RT regioselective synthesis of diverse quercetin glucosides.";
RL Biotechnol. Bioeng. 87:623-631(2004).
CC -!- FUNCTION: Possesses low quercetin 3-O-glucosyltransferase and 7-O-
CC glucosyltransferase activities in vitro. {ECO:0000269|PubMed:15352060}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000305}.
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DR EMBL; AL133314; CAB62337.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78192.1; -; Genomic_DNA.
DR EMBL; AY080716; AAL85034.1; -; mRNA.
DR EMBL; AY117336; AAM51411.1; -; mRNA.
DR EMBL; AY084880; AAM61443.1; -; mRNA.
DR PIR; T45604; T45604.
DR RefSeq; NP_190251.1; NM_114534.3.
DR AlphaFoldDB; Q9SNB1; -.
DR SMR; Q9SNB1; -.
DR STRING; 3702.AT3G46670.1; -.
DR CAZy; GT1; Glycosyltransferase Family 1.
DR PaxDb; Q9SNB1; -.
DR PRIDE; Q9SNB1; -.
DR ProteomicsDB; 228644; -.
DR EnsemblPlants; AT3G46670.1; AT3G46670.1; AT3G46670.
DR GeneID; 823820; -.
DR Gramene; AT3G46670.1; AT3G46670.1; AT3G46670.
DR KEGG; ath:AT3G46670; -.
DR Araport; AT3G46670; -.
DR TAIR; locus:2075120; AT3G46670.
DR eggNOG; KOG1192; Eukaryota.
DR HOGENOM; CLU_001724_0_0_1; -.
DR InParanoid; Q9SNB1; -.
DR OMA; TEEDKCI; -.
DR OrthoDB; 508327at2759; -.
DR PhylomeDB; Q9SNB1; -.
DR PRO; PR:Q9SNB1; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SNB1; differential.
DR Genevisible; Q9SNB1; AT.
DR GO; GO:0080043; F:quercetin 3-O-glucosyltransferase activity; IDA:TAIR.
DR GO; GO:0080044; F:quercetin 7-O-glucosyltransferase activity; IDA:TAIR.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR InterPro; IPR002213; UDP_glucos_trans.
DR Pfam; PF00201; UDPGT; 1.
PE 2: Evidence at transcript level;
KW Glycosyltransferase; Reference proteome; Transferase.
FT CHAIN 1..451
FT /note="UDP-glycosyltransferase 76E11"
FT /id="PRO_0000409094"
FT BINDING 273
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 332..334
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 349..357
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 371..374
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT CONFLICT 2
FT /note="E -> D (in Ref. 4; AAM61443)"
FT /evidence="ECO:0000305"
FT CONFLICT 11
FT /note="V -> M (in Ref. 4; AAM61443)"
FT /evidence="ECO:0000305"
FT CONFLICT 342
FT /note="A -> V (in Ref. 4; AAM61443)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 451 AA; 50564 MW; C84091DBE664ADD9 CRC64;
MEEKPAGRRV VLVAVPAQGH ISPIMQLAKT LHLKGFSITI AQTKFNYFSP SDDFTDFQFV
TIPESLPESD FEDLGPIEFL HKLNKECQVS FKDCLGQLLL QQGNEIACVV YDEFMYFAEA
AAKEFKLPNV IFSTTSATAF VCRSAFDKLY ANSILTPLKE PKGQQNELVP EFHPLRCKDF
PVSHWASLES MMELYRNTVD KRTASSVIIN TASCLESSSL SRLQQQLQIP VYPIGPLHLV
ASASTSLLEE NKSCIEWLNK QKKNSVIFVS LGSLALMEIN EVIETALGLD SSKQQFLWVI
RPGSVRGSEW IENLPKEFSK IISGRGYIVK WAPQKEVLSH PAVGGFWSHC GWNSTLESIG
EGVPMICKPF SSDQMVNARY LECVWKIGIQ VEGDLDRGAV ERAVRRLMVE EEGEGMRKRA
ISLKEQLRAS VISGGSSHNS LEEFVHYMRT L
