U84B1_ARATH
ID U84B1_ARATH Reviewed; 456 AA.
AC O22182;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=UDP-glycosyltransferase 84B1;
DE EC=2.4.1.-;
GN Name=UGT84B1; OrderedLocusNames=At2g23260; ORFNames=T20D16.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=11042215; DOI=10.1074/jbc.m007447200;
RA Li Y., Baldauf S., Lim E.K., Bowles D.J.;
RT "Phylogenetic analysis of the UDP-glycosyltransferase multigene family of
RT Arabidopsis thaliana.";
RL J. Biol. Chem. 276:4338-4343(2001).
RN [6]
RP FUNCTION.
RX PubMed=15352060; DOI=10.1002/bit.20154;
RA Lim E.K., Ashford D.A., Hou B., Jackson R.G., Bowles D.J.;
RT "Arabidopsis glycosyltransferases as biocatalysts in fermentation for
RT regioselective synthesis of diverse quercetin glucosides.";
RL Biotechnol. Bioeng. 87:623-631(2004).
CC -!- FUNCTION: Possesses low quercetin 7-O-glucosyltransferase activity in
CC vitro. {ECO:0000269|PubMed:15352060}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000305}.
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DR EMBL; AC002391; AAB87119.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07435.1; -; Genomic_DNA.
DR EMBL; AK118431; BAC43040.1; -; mRNA.
DR EMBL; BT005368; AAO63432.1; -; mRNA.
DR PIR; T00506; T00506.
DR RefSeq; NP_179907.1; NM_127890.3.
DR AlphaFoldDB; O22182; -.
DR SMR; O22182; -.
DR STRING; 3702.AT2G23260.1; -.
DR CAZy; GT1; Glycosyltransferase Family 1.
DR PaxDb; O22182; -.
DR PRIDE; O22182; -.
DR ProteomicsDB; 242811; -.
DR EnsemblPlants; AT2G23260.1; AT2G23260.1; AT2G23260.
DR GeneID; 816858; -.
DR Gramene; AT2G23260.1; AT2G23260.1; AT2G23260.
DR KEGG; ath:AT2G23260; -.
DR Araport; AT2G23260; -.
DR TAIR; locus:2058563; AT2G23260.
DR eggNOG; KOG1192; Eukaryota.
DR HOGENOM; CLU_001724_0_1_1; -.
DR InParanoid; O22182; -.
DR OMA; WIPEDSC; -.
DR OrthoDB; 508327at2759; -.
DR PhylomeDB; O22182; -.
DR BioCyc; ARA:AT2G23260-MON; -.
DR BioCyc; MetaCyc:AT2G23260-MON; -.
DR SABIO-RK; O22182; -.
DR PRO; PR:O22182; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O22182; baseline and differential.
DR Genevisible; O22182; AT.
DR GO; GO:0047215; F:indole-3-acetate beta-glucosyltransferase activity; IDA:TAIR.
DR GO; GO:0080043; F:quercetin 3-O-glucosyltransferase activity; IBA:GO_Central.
DR GO; GO:0080044; F:quercetin 7-O-glucosyltransferase activity; IDA:TAIR.
DR GO; GO:0035251; F:UDP-glucosyltransferase activity; IDA:TAIR.
DR GO; GO:0090354; P:regulation of auxin metabolic process; IMP:TAIR.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR Pfam; PF00201; UDPGT; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 2: Evidence at transcript level;
KW Glycosyltransferase; Reference proteome; Transferase.
FT CHAIN 1..456
FT /note="UDP-glycosyltransferase 84B1"
FT /id="PRO_0000409124"
FT BINDING 278
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 332..334
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 349..357
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 371..374
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
SQ SEQUENCE 456 AA; 50714 MW; 6770DA38A7709602 CRC64;
MGSSEGQETH VLMVTLPFQG HINPMLKLAK HLSLSSKNLH INLATIESAR DLLSTVEKPR
YPVDLVFFSD GLPKEDPKAP ETLLKSLNKV GAMNLSKIIE EKRYSCIISS PFTPWVPAVA
ASHNISCAIL WIQACGAYSV YYRYYMKTNS FPDLEDLNQT VELPALPLLE VRDLPSFMLP
SGGAHFYNLM AEFADCLRYV KWVLVNSFYE LESEIIESMA DLKPVIPIGP LVSPFLLGDG
EEETLDGKNL DFCKSDDCCM EWLDKQARSS VVYISFGSML ETLENQVETI AKALKNRGLP
FLWVIRPKEK AQNVAVLQEM VKEGQGVVLE WSPQEKILSH EAISCFVTHC GWNSTMETVV
AGVPVVAYPS WTDQPIDARL LVDVFGIGVR MRNDSVDGEL KVEEVERCIE AVTEGPAAVD
IRRRAAELKR VARLALAPGG SSTRNLDLFI SDITIA
