U85A3_ARATH
ID U85A3_ARATH Reviewed; 488 AA.
AC Q9LMF1;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 31-MAY-2011, sequence version 2.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=UDP-glycosyltransferase 85A3;
DE EC=2.4.1.-;
GN Name=UGT85A3; OrderedLocusNames=At1g22380; ORFNames=F12K8.28, T16E15.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=11042215; DOI=10.1074/jbc.m007447200;
RA Li Y., Baldauf S., Lim E.K., Bowles D.J.;
RT "Phylogenetic analysis of the UDP-glycosyltransferase multigene family of
RT Arabidopsis thaliana.";
RL J. Biol. Chem. 276:4338-4343(2001).
RN [4]
RP TISSUE SPECIFICITY.
RX PubMed=17498920; DOI=10.1016/j.ygeno.2007.03.014;
RA Woo H.H., Jeong B.R., Hirsch A.M., Hawes M.C.;
RT "Characterization of Arabidopsis AtUGT85A and AtGUS gene families and their
RT expression in rapidly dividing tissues.";
RL Genomics 90:143-153(2007).
CC -!- TISSUE SPECIFICITY: Expressed in roots and flowers.
CC {ECO:0000269|PubMed:17498920}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000305}.
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DR EMBL; AC006551; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC068562; AAF87254.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30236.1; -; Genomic_DNA.
DR PIR; G86356; G86356.
DR RefSeq; NP_173655.2; NM_102088.3.
DR AlphaFoldDB; Q9LMF1; -.
DR SMR; Q9LMF1; -.
DR STRING; 3702.AT1G22380.1; -.
DR CAZy; GT1; Glycosyltransferase Family 1.
DR PaxDb; Q9LMF1; -.
DR PRIDE; Q9LMF1; -.
DR ProteomicsDB; 228681; -.
DR EnsemblPlants; AT1G22380.1; AT1G22380.1; AT1G22380.
DR GeneID; 838845; -.
DR Gramene; AT1G22380.1; AT1G22380.1; AT1G22380.
DR KEGG; ath:AT1G22380; -.
DR Araport; AT1G22380; -.
DR TAIR; locus:2196490; AT1G22380.
DR eggNOG; KOG1192; Eukaryota.
DR HOGENOM; CLU_001724_0_0_1; -.
DR InParanoid; Q9LMF1; -.
DR OMA; MGSHVVC; -.
DR OrthoDB; 508327at2759; -.
DR PRO; PR:Q9LMF1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LMF1; baseline and differential.
DR Genevisible; Q9LMF1; AT.
DR GO; GO:0015020; F:glucuronosyltransferase activity; ISS:TAIR.
DR GO; GO:0080043; F:quercetin 3-O-glucosyltransferase activity; IBA:GO_Central.
DR GO; GO:0080044; F:quercetin 7-O-glucosyltransferase activity; IBA:GO_Central.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR Pfam; PF00201; UDPGT; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 2: Evidence at transcript level;
KW Glycosyltransferase; Reference proteome; Transferase.
FT CHAIN 1..488
FT /note="UDP-glycosyltransferase 85A3"
FT /id="PRO_0000409127"
FT BINDING 306
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 363..365
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 380..388
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 402..405
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
SQ SEQUENCE 488 AA; 54609 MW; 6E0BDA33A1605C45 CRC64;
MGSRFVSNEQ KPHVVCVPYP AQGHINPMMK VAKLLHVKGF HVTFVNTVYN HNRLLRSRGA
NALDGLPSFQ FESIPDGLPE TGVDATQDIP ALSESTTKNC LVPFKKLLQR IVTREDVPPV
SCIVSDGSMS FTLDVAEELG VPEIHFWTTS ACGFMAYLHF YLFIEKGLCP VKDASCLTKE
YLDTVIDWIP SMNNVKLKDI PSFIRTTNPN DIMLNFVVRE ACRTKRASAI ILNTFDDLEH
DIIQSMQSIL PPVYPIGPLH LLVNREIEED SEIGRMGSNL WKEETECLGW LNTKSRNSVV
YVNFGSITIM TTAQLLEFAW GLAATGKEFL WVMRPDSVAG EEAVIPKEFL AETADRRMLT
SWCPQEKVLS HPAVGGFLTH CGWNSTLESL SCGVPMVCWP FFAEQQTNCK FSCDEWEVGI
EIGGDVKRGE VEAVVRELMD GEKGKKMREK AVEWRRLAEK ATKLPCGSSV INFETIVNKV
LLGKIPNT
