U85A7_ARATH
ID U85A7_ARATH Reviewed; 487 AA.
AC Q9LME8;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=UDP-glycosyltransferase 85A7;
DE EC=2.4.1.-;
GN Name=UGT85A7; OrderedLocusNames=At1g22340; ORFNames=T16E15.5;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP GENE FAMILY.
RX PubMed=11042215; DOI=10.1074/jbc.m007447200;
RA Li Y., Baldauf S., Lim E.K., Bowles D.J.;
RT "Phylogenetic analysis of the UDP-glycosyltransferase multigene family of
RT Arabidopsis thaliana.";
RL J. Biol. Chem. 276:4338-4343(2001).
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=17498920; DOI=10.1016/j.ygeno.2007.03.014;
RA Woo H.H., Jeong B.R., Hirsch A.M., Hawes M.C.;
RT "Characterization of Arabidopsis AtUGT85A and AtGUS gene families and their
RT expression in rapidly dividing tissues.";
RL Genomics 90:143-153(2007).
CC -!- TISSUE SPECIFICITY: Expressed in roots, shoots, leaves and flowers.
CC {ECO:0000269|PubMed:17498920}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000305}.
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DR EMBL; AC068562; AAF87257.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30231.1; -; Genomic_DNA.
DR EMBL; DQ446278; ABE65644.1; -; mRNA.
DR PIR; C86356; C86356.
DR RefSeq; NP_173652.1; NM_102085.3.
DR AlphaFoldDB; Q9LME8; -.
DR SMR; Q9LME8; -.
DR STRING; 3702.AT1G22340.1; -.
DR CAZy; GT1; Glycosyltransferase Family 1.
DR iPTMnet; Q9LME8; -.
DR PaxDb; Q9LME8; -.
DR PRIDE; Q9LME8; -.
DR ProteomicsDB; 242814; -.
DR EnsemblPlants; AT1G22340.1; AT1G22340.1; AT1G22340.
DR GeneID; 838841; -.
DR Gramene; AT1G22340.1; AT1G22340.1; AT1G22340.
DR KEGG; ath:AT1G22340; -.
DR Araport; AT1G22340; -.
DR TAIR; locus:2196516; AT1G22340.
DR eggNOG; KOG1192; Eukaryota.
DR HOGENOM; CLU_001724_0_0_1; -.
DR InParanoid; Q9LME8; -.
DR OMA; EFECVEW; -.
DR OrthoDB; 508327at2759; -.
DR PhylomeDB; Q9LME8; -.
DR BioCyc; ARA:AT1G22340-MON; -.
DR PRO; PR:Q9LME8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LME8; baseline and differential.
DR Genevisible; Q9LME8; AT.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0015020; F:glucuronosyltransferase activity; ISS:TAIR.
DR GO; GO:0080043; F:quercetin 3-O-glucosyltransferase activity; IBA:GO_Central.
DR GO; GO:0080044; F:quercetin 7-O-glucosyltransferase activity; IBA:GO_Central.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR Pfam; PF00201; UDPGT; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 2: Evidence at transcript level;
KW Glycosyltransferase; Reference proteome; Transferase.
FT CHAIN 1..487
FT /note="UDP-glycosyltransferase 85A7"
FT /id="PRO_0000409130"
FT BINDING 364..366
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 381..389
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 403..406
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
SQ SEQUENCE 487 AA; 55456 MW; E5AB7844464B26E6 CRC64;
MESHVVHNAQ KPHVVCVPYP AQGHINPMLK VAKLLYAKGF HVTFVNTLYN HNRLLRSRGP
NALDGFPSFR FESIPDGLPE TDGDRTQHTP TVCMSIEKNC LAPFKEILRR INDKDDVPPV
SCIVSDGVMS FTLDAAEELG VPEVIFWTNS ACGFMTILHF YLFIEKGLSP FKDESYMSKE
HLDTVIDWIP SMKNLRLKDI PSYIRTTNPD NIMLNFLIRE VERSKRASAI ILNTFDELEH
DVIQSMQSIL PPVYSIGPLH LLVKEEINEA SEIGQMGLNL WREEMECLDW LDTKTPNSVL
FVNFGCITVM SAKQLEEFAW GLAASRKEFL WVIRPNLVVG EAMVVLPQEF LAETIDRRML
ASWCPQEKVL SHPAIGGFLT HCGWNSTLES LAGGVPMICW PCFSEQPTNC KFCCDEWGVG
IEIGKDVKRE EVETVVRELM DGEKGKKLRE KAEEWRRLAE EATRYKHGSS VMNLETLIHK
VFLENLR
