ID   U89A2_ARATH             Reviewed;         465 AA.
AC   Q9LZD8;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=UDP-glycosyltransferase 89A2;
DE            EC=2.4.1.-;
GN   Name=UGT89A2; OrderedLocusNames=At5g03490; ORFNames=F12E4.260;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA   Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA   Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA   O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA   Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA   Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA   Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA   Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA   Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA   Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA   Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA   McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA   Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA   Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA   Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA   Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA   Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL   Nature 408:823-826(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=11042215; DOI=10.1074/jbc.m007447200;
RA   Li Y., Baldauf S., Lim E.K., Bowles D.J.;
RT   "Phylogenetic analysis of the UDP-glycosyltransferase multigene family of
RT   Arabidopsis thaliana.";
RL   J. Biol. Chem. 276:4338-4343(2001).
RN   [4]
RP   FUNCTION.
RX   PubMed=11641410; DOI=10.1074/jbc.m109287200;
RA   Lim E.K., Doucet C.J., Li Y., Elias L., Worrall D., Spencer S.P., Ross J.,
RA   Bowles D.J.;
RT   "The activity of Arabidopsis glycosyltransferases toward salicylic acid, 4-
RT   hydroxybenzoic acid, and other benzoates.";
RL   J. Biol. Chem. 277:586-592(2002).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT   "Arabidopsis ORF Clones.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Glucosyltransferase that glucosylates benzoates and benzoate
CC       derivatives in vitro. {ECO:0000269|PubMed:11641410}.
CC   -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC       {ECO:0000305}.
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DR   EMBL; AL162751; CAB83309.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED90611.1; -; Genomic_DNA.
DR   EMBL; BT026358; ABH04465.1; -; mRNA.
DR   PIR; T48374; T48374.
DR   RefSeq; NP_195969.1; NM_120429.4.
DR   AlphaFoldDB; Q9LZD8; -.
DR   SMR; Q9LZD8; -.
DR   STRING; 3702.AT5G03490.1; -.
DR   CAZy; GT1; Glycosyltransferase Family 1.
DR   PaxDb; Q9LZD8; -.
DR   PRIDE; Q9LZD8; -.
DR   ProteomicsDB; 228595; -.
DR   EnsemblPlants; AT5G03490.1; AT5G03490.1; AT5G03490.
DR   GeneID; 831823; -.
DR   Gramene; AT5G03490.1; AT5G03490.1; AT5G03490.
DR   KEGG; ath:AT5G03490; -.
DR   Araport; AT5G03490; -.
DR   TAIR; locus:2142654; AT5G03490.
DR   eggNOG; KOG1192; Eukaryota.
DR   HOGENOM; CLU_001724_2_2_1; -.
DR   InParanoid; Q9LZD8; -.
DR   OMA; NPPIALI; -.
DR   OrthoDB; 508327at2759; -.
DR   PhylomeDB; Q9LZD8; -.
DR   BioCyc; ARA:AT5G03490-MON; -.
DR   PRO; PR:Q9LZD8; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9LZD8; baseline and differential.
DR   Genevisible; Q9LZD8; AT.
DR   GO; GO:0035251; F:UDP-glucosyltransferase activity; IDA:TAIR.
DR   GO; GO:0008194; F:UDP-glycosyltransferase activity; IMP:TAIR.
DR   CDD; cd03784; GT1_Gtf-like; 1.
DR   InterPro; IPR002213; UDP_glucos_trans.
DR   Pfam; PF00201; UDPGT; 1.
PE   2: Evidence at transcript level;
KW   Glycosyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..465
FT                   /note="UDP-glycosyltransferase 89A2"
FT                   /id="PRO_0000409136"
FT   BINDING         291
FT                   /ligand="UDP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:58885"
FT                   /evidence="ECO:0000250"
FT   BINDING         342..344
FT                   /ligand="UDP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:58885"
FT                   /evidence="ECO:0000250"
FT   BINDING         359..367
FT                   /ligand="UDP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:58885"
FT                   /evidence="ECO:0000250"
FT   BINDING         381..384
FT                   /ligand="UDP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:58885"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   465 AA;  50942 MW;  3C21B5165CAF6A37 CRC64;
     MTEVLLLPGT KSENSKPPHI VVFPFPAQGH LLPLLDLTHQ LCLRGFNVSV IVTPGNLTYL
     SPLLSAHPSS VTSVVFPFPP HPSLSPGVEN VKDVGNSGNL PIMASLRQLR EPIINWFQSH
     PNPPIALISD FFLGWTHDLC NQIGIPRFAF FSISFFLVSV LQFCFENIDL IKSTDPIHLL
     DLPRAPIFKE EHLPSIVRRS LQTPSPDLES IKDFSMNLLS YGSVFNSSEI LEDDYLQYVK
     QRMGHDRVYV IGPLCSIGSG LKSNSGSVDP SLLSWLDGSP NGSVLYVCFG SQKALTKDQC
     DALALGLEKS MTRFVWVVKK DPIPDGFEDR VSGRGLVVRG WVSQLAVLRH VAVGGFLSHC
     GWNSVLEGIT SGAVILGWPM EADQFVNARL LVEHLGVAVR VCEGGETVPD SDELGRVIAE
     TMGEGGREVA ARAEEIRRKT EAAVTEANGS SVENVQRLVK EFEKV