U90A1_ARATH
ID U90A1_ARATH Reviewed; 478 AA.
AC Q9ZVX4; Q8LED6; Q93Y26;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=UDP-glycosyltransferase 90A1;
DE EC=2.4.1.-;
GN Name=UGT90A1; OrderedLocusNames=At2g16890; ORFNames=F12A24.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=11042215; DOI=10.1074/jbc.m007447200;
RA Li Y., Baldauf S., Lim E.K., Bowles D.J.;
RT "Phylogenetic analysis of the UDP-glycosyltransferase multigene family of
RT Arabidopsis thaliana.";
RL J. Biol. Chem. 276:4338-4343(2001).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9ZVX4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9ZVX4-2; Sequence=VSP_041237, VSP_041238;
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000305}.
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DR EMBL; AC005167; AAC64220.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06548.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06549.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM61779.1; -; Genomic_DNA.
DR EMBL; AY054598; AAK96789.1; -; mRNA.
DR EMBL; BT002606; AAO00966.1; -; mRNA.
DR EMBL; AY085480; AAM62706.1; -; mRNA.
DR PIR; E84545; E84545.
DR RefSeq; NP_001318233.1; NM_001335496.1. [Q9ZVX4-2]
DR RefSeq; NP_179281.3; NM_127242.4. [Q9ZVX4-1]
DR RefSeq; NP_850992.1; NM_180661.2. [Q9ZVX4-2]
DR AlphaFoldDB; Q9ZVX4; -.
DR SMR; Q9ZVX4; -.
DR BioGRID; 1547; 1.
DR IntAct; Q9ZVX4; 1.
DR STRING; 3702.AT2G16890.2; -.
DR CAZy; GT1; Glycosyltransferase Family 1.
DR iPTMnet; Q9ZVX4; -.
DR PaxDb; Q9ZVX4; -.
DR PRIDE; Q9ZVX4; -.
DR ProteomicsDB; 228686; -. [Q9ZVX4-1]
DR EnsemblPlants; AT2G16890.1; AT2G16890.1; AT2G16890. [Q9ZVX4-2]
DR EnsemblPlants; AT2G16890.2; AT2G16890.2; AT2G16890. [Q9ZVX4-1]
DR EnsemblPlants; AT2G16890.4; AT2G16890.4; AT2G16890. [Q9ZVX4-2]
DR GeneID; 816190; -.
DR Gramene; AT2G16890.1; AT2G16890.1; AT2G16890. [Q9ZVX4-2]
DR Gramene; AT2G16890.2; AT2G16890.2; AT2G16890. [Q9ZVX4-1]
DR Gramene; AT2G16890.4; AT2G16890.4; AT2G16890. [Q9ZVX4-2]
DR KEGG; ath:AT2G16890; -.
DR Araport; AT2G16890; -.
DR TAIR; locus:2039425; AT2G16890.
DR eggNOG; KOG1192; Eukaryota.
DR HOGENOM; CLU_001724_2_2_1; -.
DR InParanoid; Q9ZVX4; -.
DR OMA; PVEELML; -.
DR OrthoDB; 508327at2759; -.
DR PhylomeDB; Q9ZVX4; -.
DR BioCyc; ARA:AT2G16890-MON; -.
DR PRO; PR:Q9ZVX4; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZVX4; baseline and differential.
DR Genevisible; Q9ZVX4; AT.
DR GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR Pfam; PF00201; UDPGT; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Glycosyltransferase; Reference proteome; Transferase.
FT CHAIN 1..478
FT /note="UDP-glycosyltransferase 90A1"
FT /id="PRO_0000409139"
FT BINDING 289
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 343..345
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 360..368
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT BINDING 382..385
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250"
FT VAR_SEQ 311..312
FT /note="NF -> RT (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14593172"
FT /id="VSP_041237"
FT VAR_SEQ 313..478
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14593172"
FT /id="VSP_041238"
FT CONFLICT 15
FT /note="F -> Y (in Ref. 4; AAM62706)"
FT /evidence="ECO:0000305"
FT CONFLICT 88
FT /note="K -> R (in Ref. 4; AAM62706)"
FT /evidence="ECO:0000305"
FT CONFLICT 187
FT /note="V -> I (in Ref. 4; AAM62706)"
FT /evidence="ECO:0000305"
FT CONFLICT 466
FT /note="E -> D (in Ref. 4; AAM62706)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 478 AA; 53747 MW; 3778391C05D7C879 CRC64;
MSVSTHHHHV VLFPFMSKGH IIPLLQFGRL LLRHHRKEPT ITVTVFTTPK NQPFISDFLS
DTPEIKVISL PFPENITGIP PGVENTEKLP SMSLFVPFTR ATKLLQPFFE ETLKTLPKVS
FMVSDGFLWW TSESAAKFNI PRFVSYGMNS YSAAVSISVF KHELFTEPES KSDTEPVTVP
DFPWIKVKKC DFDHGTTEPE ESGAALELSM DQIKSTTTSH GFLVNSFYEL ESAFVDYNNN
SGDKPKSWCV GPLCLTDPPK QGSAKPAWIH WLDQKREEGR PVLYVAFGTQ AEISNKQLME
LAFGLEDSKV NFLWVTRKDV EEIIGEGFND RIRESGMIVR DWVDQWEILS HESVKGFLSH
CGWNSAQESI CVGVPLLAWP MMAEQPLNAK MVVEEIKVGV RVETEDGSVK GFVTREELSG
KIKELMEGET GKTARKNVKE YSKMAKAALV EGTGSSWKNL DMILKELCKS RDSNGASE
