ID   ACBP_MANSE              Reviewed;          90 AA.
AC   P31824;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Acyl-CoA-binding protein homolog;
DE            Short=ACBP;
DE   AltName: Full=Diazepam-binding inhibitor homolog;
DE            Short=DBI;
OS   Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Sphingidae; Sphinginae; Sphingini; Manduca.
OX   NCBI_TaxID=7130;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Midgut;
RX   PubMed=8375571; DOI=10.1016/0303-7207(93)90064-q;
RA   Snyder M.J., Feyereisen R.;
RT   "A diazepam binding inhibitor (DBI) homolog from the tobacco hornworm,
RT   Manduca sexta.";
RL   Mol. Cell. Endocrinol. 94:R1-R4(1993).
CC   -!- FUNCTION: Binds medium- and long-chain acyl-CoA esters with very high
CC       affinity and may function as an intracellular carrier of acyl-CoA
CC       esters.
CC   -!- SIMILARITY: Belongs to the ACBP family. {ECO:0000305}.
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DR   EMBL; L11449; AAA29309.1; -; mRNA.
DR   EMBL; S65642; AAB28237.2; -; mRNA.
DR   AlphaFoldDB; P31824; -.
DR   SMR; P31824; -.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.80.10; -; 1.
DR   InterPro; IPR022408; Acyl-CoA-binding_prot_CS.
DR   InterPro; IPR000582; Acyl-CoA-binding_protein.
DR   InterPro; IPR035984; Acyl-CoA-binding_sf.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR   Pfam; PF00887; ACBP; 1.
DR   PRINTS; PR00689; ACOABINDINGP.
DR   SUPFAM; SSF47027; SSF47027; 1.
DR   PROSITE; PS00880; ACB_1; 1.
DR   PROSITE; PS51228; ACB_2; 1.
PE   3: Inferred from homology;
KW   Lipid-binding; Transport.
FT   CHAIN           1..90
FT                   /note="Acyl-CoA-binding protein homolog"
FT                   /id="PRO_0000214011"
FT   DOMAIN          3..89
FT                   /note="ACB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00573"
FT   BINDING         15
FT                   /ligand="an acyl-CoA"
FT                   /ligand_id="ChEBI:CHEBI:58342"
FT                   /evidence="ECO:0000250"
FT   BINDING         30..34
FT                   /ligand="an acyl-CoA"
FT                   /ligand_id="ChEBI:CHEBI:58342"
FT                   /evidence="ECO:0000250"
FT   BINDING         53
FT                   /ligand="an acyl-CoA"
FT                   /ligand_id="ChEBI:CHEBI:58342"
FT                   /evidence="ECO:0000250"
FT   BINDING         57
FT                   /ligand="an acyl-CoA"
FT                   /ligand_id="ChEBI:CHEBI:58342"
FT                   /evidence="ECO:0000250"
FT   BINDING         76
FT                   /ligand="an acyl-CoA"
FT                   /ligand_id="ChEBI:CHEBI:58342"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   90 AA;  9774 MW;  6F67E2838265FCAA CRC64;
     MSLQEQFDQA ASNVRNLKSL PSDNDLLELY ALFKQASAGD ADPANRPGLL DLKGKAKFDA
     WHKKAGLSKE DAQKAYIAKV ESLIASLGLQ