ID   C77A3_SOYBN             Reviewed;         513 AA.
AC   O48928;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Cytochrome P450 77A3;
DE            EC=1.14.-.-;
GN   Name=CYP77A3;
OS   Glycine max (Soybean) (Glycine hispida).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC   Glycine subgen. Soja.
OX   NCBI_TaxID=3847;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Siminszky B., Dewey R.E., Corbin F.T.;
RL   Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF022464; AAB94593.1; -; mRNA.
DR   PIR; T05948; T05948.
DR   AlphaFoldDB; O48928; -.
DR   SMR; O48928; -.
DR   STRING; 3847.GLYMA20G32930.1; -.
DR   eggNOG; KOG0156; Eukaryota.
DR   InParanoid; O48928; -.
DR   Proteomes; UP000008827; Unplaced.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IBA:GO_Central.
DR   Gene3D; 1.10.630.10; -; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; SSF48264; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   2: Evidence at transcript level;
KW   Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase;
KW   Reference proteome.
FT   CHAIN           1..513
FT                   /note="Cytochrome P450 77A3"
FT                   /id="PRO_0000052147"
FT   BINDING         451
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   513 AA;  58132 MW;  D33F898F2951F6C6 CRC64;
     MATLSSYDHF IFTALAFFIS GLIFFLKQKS KSKKFNLPPG PPGWPIVGNL FQVARSGKPF
     FEYVNDVRLK YGSIFTLKMG TRTMIILTDA KLVHEAMIQK GATYATRPPE NPTRTIFSEN
     KFTVNAATYG PVWKSLRRNM VQNMLSSTRL KEFRSVRDNA MDKLINRLKD EAEKNNGVVW
     VLKDARFAVF CILVAMCFGL EMDEETVERI DQVMKSVLIT LDPRIDDYLP ILSPFFSKQR
     KKALEVRREQ VEFLVPIIEQ RRRAIQNPGS DHTATTFSYL DTLFDLKVEG KKSAPSDAEL
     VSLCSEFLNG GTDTTATAVE WGIAQLIANP NVQTKLYEEI KRTVGEKKVD EKDVEKMPYL
     HAVVKELLRK HPPTHFVLTH AVTEPTTLGG YDIPIDANVE VYTPAIAEDP KNWLNPEKFD
     PERFISGGEE ADITGVTGVK MMPFGVGRRI CPGLAMATVH IHLMMARMVQ EFEWGAYPPE
     KKMDFTGKWE FTVVMKESLR ATIKPRGGEK VKL