ID   C78A1_MAIZE             Reviewed;         547 AA.
AC   P48420;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Cytochrome P450 78A1;
DE            EC=1.14.-.-;
DE   AltName: Full=CYPLXXVIII;
GN   Name=CYP78A1; Synonyms=CYP78;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Flower;
RX   PubMed=8049361; DOI=10.1007/bf00043864;
RA   Larkin J.C.;
RT   "Isolation of a cytochrome P450 homologue preferentially expressed in
RT   developing inflorescences of Zea mays.";
RL   Plant Mol. Biol. 25:343-353(1994).
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC   -!- TISSUE SPECIFICITY: Shoot apex.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR   EMBL; L23209; AAA61607.1; -; mRNA.
DR   PIR; S51475; S51475.
DR   AlphaFoldDB; P48420; -.
DR   SMR; P48420; -.
DR   STRING; 4577.GRMZM2G167986_P01; -.
DR   PRIDE; P48420; -.
DR   KEGG; ag:AAA61607; -.
DR   MaizeGDB; 51340; -.
DR   eggNOG; KOG0156; Eukaryota.
DR   Proteomes; UP000007305; Unplaced.
DR   ExpressionAtlas; P48420; differential.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   GO; GO:0090709; P:regulation of timing of plant organ formation; IEA:EnsemblPlants.
DR   Gene3D; 1.10.630.10; -; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; SSF48264; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   2: Evidence at transcript level;
KW   Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase;
KW   Reference proteome.
FT   CHAIN           1..547
FT                   /note="Cytochrome P450 78A1"
FT                   /id="PRO_0000052148"
FT   REGION          84..104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         490
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   547 AA;  58400 MW;  1DF9AF44739B7328 CRC64;
     MAMASAACSC TDGTWWVYAL PALLGSDTLC AHPALLAGLI FLATVSVALL AWATSPGGPA
     WTNGRGASAS LLSWDPVVCP CSAASSRCPG AAAPRPRRDG PRRRPRAKEL MAFSVGDTPA
     VVSSCPATAR EVLAHPSFAD RPVKRSAREL MFARAIGFAP NGEYWRRLRR VASTHLFSPR
     RVASHEPGRQ GDAEAMLRSI AAEQSASGAV ALRPHLQAAA LNNIMGSVFG TRYDVTSGAG
     AAEAEHLKSM VREGFELLGA FNWSDHLPWL AHLYDPSNVT RRCAALVPRV QTFVRGVIDE
     HRRRRQNSAA LNDNADFVDV LLSLEGDEKL GDDDMVAILW EMVFRGTDTT ALLTEWCMAE
     LVRHPAVQAR VRAEVDAAVG AGGCPTDADV ARMPYLQAVV KETLRAHPPG PLLSWARLAT
     ADVPLCNGMV VPAGTTAMVN MWAITHDAAV WADPDAFAPE RFLPSEGGAD VDVRGVDLRL
     APFGAGRRVC PGKNLGLTTV GLWVARLVHA FQWALPDGAA AVCLDEVLKL SLEMKTPLVA
     AAIPRTA