UBA1B_ARATH
ID UBA1B_ARATH Reviewed; 382 AA.
AC Q9SHZ5; Q8L9T4;
DT 19-FEB-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 2.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=UBP1-associated proteins 1B;
GN Name=UBA1B; OrderedLocusNames=At2g22100; ORFNames=T16B14.5;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as component of a complex regulating the turnover of
CC mRNAs in the nucleus. Binds with high affinity to RNA molecules that
CC contain U-rich sequences in 3'-UTRs. May function in complex with UBP1
CC and contribute to the stabilization of mRNAs in the nucleus (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR EMBL; AC007232; AAD25814.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC07264.1; -; Genomic_DNA.
DR EMBL; AY088233; AAM65774.1; -; mRNA.
DR PIR; A84609; A84609.
DR RefSeq; NP_565526.1; NM_127779.2.
DR AlphaFoldDB; Q9SHZ5; -.
DR SMR; Q9SHZ5; -.
DR BioGRID; 2098; 2.
DR STRING; 3702.AT2G22100.1; -.
DR PaxDb; Q9SHZ5; -.
DR PRIDE; Q9SHZ5; -.
DR ProteomicsDB; 228593; -.
DR EnsemblPlants; AT2G22100.1; AT2G22100.1; AT2G22100.
DR GeneID; 816745; -.
DR Gramene; AT2G22100.1; AT2G22100.1; AT2G22100.
DR KEGG; ath:AT2G22100; -.
DR Araport; AT2G22100; -.
DR TAIR; locus:2055951; AT2G22100.
DR eggNOG; KOG0118; Eukaryota.
DR HOGENOM; CLU_740995_0_0_1; -.
DR InParanoid; Q9SHZ5; -.
DR OMA; GERAWYL; -.
DR OrthoDB; 1202220at2759; -.
DR PhylomeDB; Q9SHZ5; -.
DR PRO; PR:Q9SHZ5; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SHZ5; baseline and differential.
DR Genevisible; Q9SHZ5; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IBA:GO_Central.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
DR PROSITE; PS50102; RRM; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; RNA-binding.
FT CHAIN 1..382
FT /note="UBP1-associated proteins 1B"
FT /id="PRO_0000425438"
FT DOMAIN 163..248
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 1..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..78
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 246
FT /note="P -> T (in Ref. 3; AAM65774)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 382 AA; 42884 MW; C7CA5D9A3827179A CRC64;
MAKEGEERKK EKKEKKERKE RKRREAEELA VREKKISKKH KSKSKEEEKP EKSKKKSKKY
EEVEEEEKSP SPSPSPKKSK ESKKKHKRSS DESEEIVDSK PVTVPIVTIE SDSDFEFDKE
DIKNLLESYS KEELINLIYK TAEKGSKLIS AVFESADRDS SQRNIFVRGL GWDTTHENLK
AAFEVYGEIT ECSVVMDKDT GRAKGFGFVL FKTRKGARAA LKNPEKRMYN RTVSCLPARP
FNSGKPREQQ QPVESVKIDL SHTGNQSEMA LPGIDLGHGL DKGHQQQQNM SMYAGQNMPF
YGHSQPPPGF NPMYGAMMGN PMVAGLQNYR MFGSGMMNQG PMMPPNHMGM VGQYVGDGNV
NGVGAGAGAG AGFDGERAWY LR
