C78AB_ORYSJ
ID C78AB_ORYSJ Reviewed; 555 AA.
AC Q7Y1V5; A0A0P0XUQ2; Q0IY05; Q8LND2;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2005, sequence version 2.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Cytochrome P450 78A11;
DE EC=1.14.-.-;
DE AltName: Full=Protein PLASTOCHRON1;
GN Name=CYP78A11; Synonyms=PLA1;
GN OrderedLocusNames=Os10g0403000, LOC_Os10g26340; ORFNames=OSJNBa0044A10.17;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL
RP STAGE, MUTAGENESIS OF ALA-421 AND PRO-496, AND DISRUPTION PHENOTYPE.
RC STRAIN=cv. Nipponbare;
RX PubMed=14711998; DOI=10.1073/pnas.2636936100;
RA Miyoshi K., Ahn B.-O., Kawakatsu T., Ito Y., Itoh J., Nagato Y., Kurata N.;
RT "PLASTOCHRON1, a timekeeper of leaf initiation in rice, encodes cytochrome
RT P450.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:875-880(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12791992; DOI=10.1126/science.1083523;
RA Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S.,
RA Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D.,
RA Oates R., Palmer M., Pries G., Gibson J., Anderson H., Paradkar M.,
RA Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F.,
RA Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M.,
RA Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R.,
RA Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F.,
RA Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D.,
RA Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R.,
RA Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K.,
RA Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S.,
RA Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S.,
RA Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R.,
RA Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M.,
RA Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R.,
RA Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E.,
RA Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.;
RT "In-depth view of structure, activity, and evolution of rice chromosome
RT 10.";
RL Science 300:1566-1569(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP DISRUPTION PHENOTYPE.
RX PubMed=9724697; DOI=10.2307/3870615;
RA Itoh J., Hasegawa A., Kitano H., Nagato Y.;
RT "A recessive heterochronic mutation, plastochron1, shortens the plastochron
RT and elongates the vegetative phase in rice.";
RL Plant Cell 10:1511-1522(1998).
RN [7]
RP DISRUPTION PHENOTYPE.
RX PubMed=19337211; DOI=10.1038/cr.2009.36;
RA Wang L., Yin H., Qian Q., Yang J., Huang C., Hu X., Luo D.;
RT "NECK LEAF 1, a GATA type transcription factor, modulates organogenesis by
RT regulating the expression of multiple regulatory genes during reproductive
RT development in rice.";
RL Cell Res. 19:598-611(2009).
CC -!- FUNCTION: Involved in the regular timing (plastochron) of lateral
CC organs formation. May regulate the rate of leaf initiation and the
CC duration of vegetative phase. Seems to be redundant to the function of
CC PLASTOCHRON2, but to act in an independent pathway.
CC {ECO:0000269|PubMed:14711998}.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings, shoot apices and young
CC panicles, but not in mature leaves, calli and roots.
CC {ECO:0000269|PubMed:14711998}.
CC -!- DEVELOPMENTAL STAGE: Expressed in plastochron 0 (P0) leaf founder
CC cells, and leaf plastochrons P1, P2 and P3 primordia, but not beyond.
CC Expressed in developing bract leaves and their incipient primordia of
CC young inflorescence apices. Down-regulated in developing spikelets.
CC {ECO:0000269|PubMed:14711998}.
CC -!- DISRUPTION PHENOTYPE: Plants double the number of leaves, and leaf size
CC and plant height are reduced to about the half that of the wild-type.
CC Some inflorescence branches are converted into vegetative shoots
CC (PubMed:14711998, PubMed:9724697). Late flowering and excessive
CC vegetative growth (PubMed:19337211). {ECO:0000269|PubMed:14711998,
CC ECO:0000269|PubMed:19337211, ECO:0000269|PubMed:9724697}.
CC -!- MISCELLANEOUS: Plastochron is defined as the time interval between leaf
CC initiation events.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR EMBL; AB096259; BAC76730.1; -; mRNA.
DR EMBL; AC083943; AAM74277.1; -; Genomic_DNA.
DR EMBL; DP000086; AAP53669.1; -; Genomic_DNA.
DR EMBL; AP008216; BAF26466.1; -; Genomic_DNA.
DR EMBL; AP014966; BAT10751.1; -; Genomic_DNA.
DR RefSeq; XP_015613477.1; XM_015757991.1.
DR AlphaFoldDB; Q7Y1V5; -.
DR SMR; Q7Y1V5; -.
DR STRING; 4530.OS10T0403000-00; -.
DR PaxDb; Q7Y1V5; -.
DR PRIDE; Q7Y1V5; -.
DR EnsemblPlants; Os10t0403000-01; Os10t0403000-01; Os10g0403000.
DR GeneID; 4348574; -.
DR Gramene; Os10t0403000-01; Os10t0403000-01; Os10g0403000.
DR KEGG; osa:4348574; -.
DR eggNOG; KOG0156; Eukaryota.
DR HOGENOM; CLU_001570_4_0_1; -.
DR InParanoid; Q7Y1V5; -.
DR OMA; VDATWWA; -.
DR OrthoDB; 702827at2759; -.
DR PlantReactome; R-OSA-9627657; Regulation of leaf development.
DR Proteomes; UP000000763; Chromosome 10.
DR Proteomes; UP000059680; Chromosome 10.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR GO; GO:0090709; P:regulation of timing of plant organ formation; IMP:UniProtKB.
DR Gene3D; 1.10.630.10; -; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; SSF48264; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 1: Evidence at protein level;
KW Developmental protein; Growth regulation; Heme; Iron; Membrane;
KW Metal-binding; Monooxygenase; Oxidoreductase; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..555
FT /note="Cytochrome P450 78A11"
FT /id="PRO_0000052151"
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000255"
FT BINDING 495
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000250"
FT MUTAGEN 421
FT /note="A->V: In pla1-2; dwarf, and rapid initiation and
FT emergence of vegetative leaves."
FT /evidence="ECO:0000269|PubMed:14711998"
FT MUTAGEN 496
FT /note="P->S: In pla1-3; dwarf, and rapid initiation and
FT emergence of vegetative leaves."
FT /evidence="ECO:0000269|PubMed:14711998"
FT CONFLICT 480
FT /note="G -> D (in Ref. 1; BAC76730)"
FT /evidence="ECO:0000305"
FT CONFLICT 506
FT /note="T -> S (in Ref. 1; BAC76730)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 555 AA; 59084 MW; EE180F0616DA959B CRC64;
MAMATATASS CVDATWWAYA LPALLGADTL CAHPALLAGA VLLAFATAAV LAWAASPGGP
AWAHGRGRLG ATPIEGPRGL PVFGSIFALS RGLPHRALDA MSRDAAAPRA RELMAFSVGE
TPAVVSSCPA TAREVLAHPS FADRPLKRSA RELLFARAIG FAPSGEYWRL LRRIASTHLF
SPRRVAAHEP GRQADATAML SAMAAEQSAT GAVVLRPHLQ AAALNNIMGS VFGRRYDVSS
SSGAAADEAE QLKSMVREGF ELLGAFNWSD HLPWLAHLYD PNHVARRCAA LVPRVQAFVR
GVIRDHRLRR DSSSTAADNA DFVDVLLSLE AHENLAEDDM VAVLWEMIFR GTDTTALVTE
WCMAEVVRNP AVQARLRAEV DAAVGGDGCP SDGDVARMPY LQAVVKETLR AHPPGPLLSW
ARLATADVGL ANGMVVPAGT TAMVNMWAIT HDGEVWADPE AFAPERFIPS EGGADVDVRG
GDLRLAPFGA GRRVCPGKNL GLATVTLWVA RLVHAFDWFL PDGSPPVSLD EVLKLSLEMK
TPLAAAATPR RRRAA
