ID   UBAC1_CHICK             Reviewed;         408 AA.
AC   Q5ZJI9;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Ubiquitin-associated domain-containing protein 1;
DE            Short=UBA domain-containing protein 1;
DE   AltName: Full=E3 ubiquitin-protein ligase subunit KPC2;
DE   AltName: Full=Kip1 ubiquitination-promoting complex protein 2;
GN   Name=UBAC1; Synonyms=KPC2, UBADC1; ORFNames=RCJMB04_17l24;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Non-catalytic subunit of the KPC complex that acts as E3
CC       ubiquitin-protein ligase. {ECO:0000250}.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- SUBUNIT: Component of the KPC complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; AJ720445; CAG32104.1; -; mRNA.
DR   RefSeq; NP_001026645.1; NM_001031474.1.
DR   AlphaFoldDB; Q5ZJI9; -.
DR   SMR; Q5ZJI9; -.
DR   STRING; 9031.ENSGALP00000002626; -.
DR   PaxDb; Q5ZJI9; -.
DR   GeneID; 427754; -.
DR   KEGG; gga:427754; -.
DR   CTD; 10422; -.
DR   VEuPathDB; HostDB:geneid_427754; -.
DR   eggNOG; ENOG502QQQ6; Eukaryota.
DR   InParanoid; Q5ZJI9; -.
DR   OrthoDB; 1163759at2759; -.
DR   PhylomeDB; Q5ZJI9; -.
DR   UniPathway; UPA00143; -.
DR   PRO; PR:Q5ZJI9; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000151; C:ubiquitin ligase complex; IBA:GO_Central.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   CDD; cd14303; UBA1_KPC2; 1.
DR   CDD; cd14304; UBA2_KPC2; 1.
DR   InterPro; IPR006636; STI1_HS-bd.
DR   InterPro; IPR015940; UBA.
DR   InterPro; IPR009060; UBA-like_sf.
DR   InterPro; IPR041926; UBA1_UBAC1.
DR   InterPro; IPR041927; UBA2_UBAC1.
DR   InterPro; IPR000626; Ubiquitin-like_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   Pfam; PF00627; UBA; 2.
DR   SMART; SM00727; STI1; 1.
DR   SMART; SM00165; UBA; 2.
DR   SUPFAM; SSF46934; SSF46934; 2.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   PROSITE; PS50030; UBA; 2.
DR   PROSITE; PS50053; UBIQUITIN_2; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome; Repeat; Ubl conjugation pathway.
FT   CHAIN           1..408
FT                   /note="Ubiquitin-associated domain-containing protein 1"
FT                   /id="PRO_0000250452"
FT   DOMAIN          14..98
FT                   /note="Ubiquitin-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00214"
FT   DOMAIN          185..231
FT                   /note="UBA 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00212"
FT   DOMAIN          291..331
FT                   /note="UBA 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00212"
FT   DOMAIN          356..395
FT                   /note="STI1"
FT   REGION          100..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          235..275
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        105..119
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   408 AA;  45686 MW;  258A74D81FC5ACF3 CRC64;
     MFVQEEKIFA GKVLRLQVCT MEGAEWLEEV PEDTTVEKLK ERCLKHCVPG SLEDPKTVTH
     HKLIHATSEK VLTDSKTVLE ENIQDRDVLL LIKKRAPPPL PKMADVSAEE KRKQEQKAPD
     KDAILKATAN LPSRNVDRTV AQHNMRDFQT ELRKILVSLI EVAQKLLALN PDAVELFKKA
     NAMLDEDEED RVDEIALRQL TEMGFPESRA VKALRLNHMS VTQAMEWLIE HADDPAVDAP
     LPGQTPSEAA AEAGASSAEA TAGPSSEAGG EEAKDELTEI FKKIRRKREF RPDPRAVIAL
     MEMGFDEKEV VDALRVNNNQ QNAACEWLLG DRKPSPEDLD KGIDTNSPLF QAILENPVVQ
     LGLTNPKTLL AFEDMLENPL NSTQWMNDPE TGPVMLQISR IFQTLNRT