ID   UBFD1_MOUSE             Reviewed;         368 AA.
AC   Q78JW9;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 2.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Ubiquitin domain-containing protein UBFD1;
GN   Name=Ubfd1; Synonyms=D7Wsu128e;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=FVB/N; TISSUE=Mammary tumor;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brain, Kidney, Liver, Lung, Pancreas, Spleen, and Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
RN   [3]
RP   STRUCTURE BY NMR OF 129-217.
RG   RIKEN structural genomics initiative (RSGI);
RT   "Solution structure of the ubiquitin domain from mouse D7WSU128E protein.";
RL   Submitted (JUN-2004) to the PDB data bank.
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DR   EMBL; BC011313; AAH11313.2; -; mRNA.
DR   CCDS; CCDS21808.1; -.
DR   RefSeq; NP_613055.2; NM_138589.2.
DR   PDB; 1V86; NMR; -; A=135-216.
DR   PDBsum; 1V86; -.
DR   AlphaFoldDB; Q78JW9; -.
DR   BMRB; Q78JW9; -.
DR   SMR; Q78JW9; -.
DR   BioGRID; 205718; 35.
DR   STRING; 10090.ENSMUSP00000033158; -.
DR   iPTMnet; Q78JW9; -.
DR   PhosphoSitePlus; Q78JW9; -.
DR   EPD; Q78JW9; -.
DR   MaxQB; Q78JW9; -.
DR   PaxDb; Q78JW9; -.
DR   PeptideAtlas; Q78JW9; -.
DR   PRIDE; Q78JW9; -.
DR   ProteomicsDB; 298087; -.
DR   Antibodypedia; 55161; 149 antibodies from 22 providers.
DR   DNASU; 28018; -.
DR   Ensembl; ENSMUST00000033158; ENSMUSP00000033158; ENSMUSG00000030870.
DR   GeneID; 28018; -.
DR   KEGG; mmu:28018; -.
DR   UCSC; uc009jof.1; mouse.
DR   CTD; 56061; -.
DR   MGI; MGI:107301; Ubfd1.
DR   VEuPathDB; HostDB:ENSMUSG00000030870; -.
DR   eggNOG; KOG1872; Eukaryota.
DR   GeneTree; ENSGT00390000012857; -.
DR   HOGENOM; CLU_079085_1_0_1; -.
DR   InParanoid; Q78JW9; -.
DR   OMA; WWVLYTI; -.
DR   OrthoDB; 1199366at2759; -.
DR   PhylomeDB; Q78JW9; -.
DR   TreeFam; TF333280; -.
DR   BioGRID-ORCS; 28018; 1 hit in 73 CRISPR screens.
DR   ChiTaRS; Ubfd1; mouse.
DR   EvolutionaryTrace; Q78JW9; -.
DR   PRO; PR:Q78JW9; -.
DR   Proteomes; UP000000589; Chromosome 7.
DR   RNAct; Q78JW9; protein.
DR   Bgee; ENSMUSG00000030870; Expressed in secondary oocyte and 255 other tissues.
DR   ExpressionAtlas; Q78JW9; baseline and differential.
DR   Genevisible; Q78JW9; MM.
DR   InterPro; IPR039120; UBFD1.
DR   InterPro; IPR000626; Ubiquitin-like_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   InterPro; IPR019954; Ubiquitin_CS.
DR   PANTHER; PTHR16470; PTHR16470; 1.
DR   Pfam; PF00240; ubiquitin; 1.
DR   SMART; SM00213; UBQ; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   PROSITE; PS00299; UBIQUITIN_1; 1.
DR   PROSITE; PS50053; UBIQUITIN_2; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome.
FT   CHAIN           1..368
FT                   /note="Ubiquitin domain-containing protein UBFD1"
FT                   /id="PRO_0000283076"
FT   DOMAIN          143..218
FT                   /note="Ubiquitin-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00214"
FT   REGION          106..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          231..263
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        231..261
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   STRAND          145..151
FT                   /evidence="ECO:0007829|PDB:1V86"
FT   STRAND          154..160
FT                   /evidence="ECO:0007829|PDB:1V86"
FT   HELIX           166..177
FT                   /evidence="ECO:0007829|PDB:1V86"
FT   STRAND          187..191
FT                   /evidence="ECO:0007829|PDB:1V86"
FT   STRAND          194..197
FT                   /evidence="ECO:0007829|PDB:1V86"
FT   HELIX           198..201
FT                   /evidence="ECO:0007829|PDB:1V86"
FT   STRAND          207..211
FT                   /evidence="ECO:0007829|PDB:1V86"
SQ   SEQUENCE   368 AA;  40143 MW;  E253230620385FD2 CRC64;
     MLKRGRGRPG KRRRRVSIET STCFRPACVK LGAGAGANLR QLASSRRPLR SWWVLYTIIM
     AAAGAPDGME EPGMDTEAEA VATEAPARPL NCVEAEAAVG AAAEDSCDAR GNLQPAPAQP
     PGDPAAQASV SNGEDAGGGV GKELVDLKII WNKTKHDVKV PLDSTGSELK QKIHSITGLP
     PAMQKVMYKG LVPEDKTLRE IKVTSGAKIM VVGSTINDVL AVNTPKDAAQ QDAKAEENKK
     EPLCRQKQHR KVLDKGKPED VMPSVKGAQE RLPTVPLSGM YNKSGGKVRL TFKLEQDQLW
     IGTKERTEKL PMGSIKNVVS EPIEGHEDYH MMAFQLGPTE ASYYWVYWVP TQYVDAIKDT
     VLGKWQYF