ID   UBFL6_HUMAN             Reviewed;         400 AA.
AC   P0CB48;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Putative upstream-binding factor 1-like protein 6;
GN   Name=UBTFL6;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA   Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA   Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA   Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA   Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA   Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA   Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA   Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA   Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA   Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA   Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA   Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA   Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA   Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA   Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA   Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT   4.";
RL   Nature 434:724-731(2005).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR   EMBL; AC017099; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P0CB48; -.
DR   SMR; P0CB48; -.
DR   IntAct; P0CB48; 1.
DR   iPTMnet; P0CB48; -.
DR   PhosphoSitePlus; P0CB48; -.
DR   BioMuta; HGNC:35406; -.
DR   DMDM; 263545823; -.
DR   MassIVE; P0CB48; -.
DR   PeptideAtlas; P0CB48; -.
DR   PRIDE; P0CB48; -.
DR   ProteomicsDB; 52438; -.
DR   GeneCards; UBTFL6; -.
DR   HGNC; HGNC:35406; UBTFL6.
DR   neXtProt; NX_P0CB48; -.
DR   PharmGKB; PA164727481; -.
DR   InParanoid; P0CB48; -.
DR   PhylomeDB; P0CB48; -.
DR   PathwayCommons; P0CB48; -.
DR   SignaLink; P0CB48; -.
DR   Pharos; P0CB48; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; P0CB48; protein.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0001164; F:RNA polymerase I core promoter sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0001181; F:RNA polymerase I general transcription initiation factor activity; IBA:GO_Central.
DR   GO; GO:0045943; P:positive regulation of transcription by RNA polymerase I; IBA:GO_Central.
DR   GO; GO:0006360; P:transcription by RNA polymerase I; IBA:GO_Central.
DR   Gene3D; 1.10.30.10; -; 2.
DR   InterPro; IPR009071; HMG_box_dom.
DR   InterPro; IPR036910; HMG_box_dom_sf.
DR   Pfam; PF00505; HMG_box; 1.
DR   SMART; SM00398; HMG; 2.
DR   SUPFAM; SSF47095; SSF47095; 2.
DR   PROSITE; PS50118; HMG_BOX_2; 2.
PE   5: Uncertain;
KW   DNA-binding; Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..400
FT                   /note="Putative upstream-binding factor 1-like protein 6"
FT                   /id="PRO_0000386642"
FT   DNA_BIND        107..175
FT                   /note="HMG box 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00267"
FT   DNA_BIND        229..295
FT                   /note="HMG box 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00267"
FT   REGION          320..400
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        327..341
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        352..367
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        370..384
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   400 AA;  46551 MW;  1D48696B3717993F CRC64;
     MPAKDIKVAL PRSQGHWSNA DILRLLECME NNLPYDDNGT FSSTQSHMDW GKVAFKNFSG
     EMCRLKWLEI SCSLRKFSTL KKLVLEAKKC VKNTNKSQKG RNHPDFPKRL LTAYIRFFKE
     NWPQYSQMYP GMRSQEVTKI LSKKYKELPE QMKQKHIQDF RKEKQEFEEK LARFREEHPD
     LDQKGKKSDI CKRVQTKVQK KVQKNIEEVR SLPKTDQFFK KVKFHGEPQK PPMNGYQKFH
     QDSWSSKELQ HLSLRERMVE IGRRWQRIPQ SQKDHYKSQA ELLQKEYKVE LDLWLKTLSP
     EDYAAYKEST YAKGKNMAMM GGPAPSLKQT DPQSSSAKGL QEGFGEGQGL QAAGTEASQT
     IWVNCQVSME PEDNRKKDGE EEESSNSLDC SSGEDMEVDV