ID   C7H23_PANGI             Reviewed;         245 AA.
AC   H2DH23;
DT   19-MAR-2014, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2012, sequence version 1.
DT   25-MAY-2022, entry version 24.
DE   RecName: Full=Cytochrome P450 CYP82H23;
DE            EC=1.14.-.-;
DE   Flags: Fragment;
OS   Panax ginseng (Korean ginseng).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Apiales; Araliaceae; Panax.
OX   NCBI_TaxID=4054;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND INDUCTION.
RX   PubMed=22039120; DOI=10.1093/pcp/pcr150;
RA   Han J.Y., Kim H.J., Kwon Y.S., Choi Y.E.;
RT   "The Cyt P450 enzyme CYP716A47 catalyzes the formation of protopanaxadiol
RT   from dammarenediol-II during ginsenoside biosynthesis in Panax ginseng.";
RL   Plant Cell Physiol. 52:2062-2073(2011).
CC   -!- FUNCTION: Probable heme-thiolate monooxygenase. {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC   -!- INDUCTION: Down-regulated by methyl jasmonate (MeJA).
CC       {ECO:0000269|PubMed:22039120}.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR   EMBL; JN604544; AEY75220.1; -; mRNA.
DR   AlphaFoldDB; H2DH23; -.
DR   SMR; H2DH23; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   Gene3D; 1.10.630.10; -; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   SUPFAM; SSF48264; SSF48264; 1.
PE   2: Evidence at transcript level;
KW   Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase.
FT   CHAIN           1..>245
FT                   /note="Cytochrome P450 CYP82H23"
FT                   /id="PRO_0000425875"
FT   NON_TER         245
SQ   SEQUENCE   245 AA;  28117 MW;  E26F09207122F241 CRC64;
     MADKYGPIFS LQLGIHKTIV VSSWAVAKEC FTTHDKVFLT RPKSLAGKHM GYDHSVFLFL
     AYGPYWRDTR KLLIVELLSN RRLDVLKHVR ESEVNSFVRE MYEQWISNGG GGSKAVVEMK
     ERFGYLTMNV ILRMVAGKRY SGTEVYSDEA RRFQKALGDL LHLVVLSMVS DAVPLFGWID
     ALRGYTGEMK NTAKEIDHVL GRWLKEHRQK RETLSINESE HDFIHGMQSV MDGSQFTEHD
     TDKAI