ID   UBID_VIBCH              Reviewed;         613 AA.
AC   Q9KV48;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=3-octaprenyl-4-hydroxybenzoate carboxy-lyase;
DE            EC=4.1.1.-;
DE   AltName: Full=Polyprenyl p-hydroxybenzoate decarboxylase;
GN   Name=ubiD; OrderedLocusNames=VC_0309;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy
CC       benzoate to 2-octaprenylphenol. {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC         Evidence={ECO:0000250};
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC   -!- SUBUNIT: Homohexamer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UbiD family. {ECO:0000305}.
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DR   EMBL; AE003852; AAF93483.1; -; Genomic_DNA.
DR   PIR; G82338; G82338.
DR   RefSeq; NP_229964.1; NC_002505.1.
DR   RefSeq; WP_001009479.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9KV48; -.
DR   SMR; Q9KV48; -.
DR   STRING; 243277.VC_0309; -.
DR   DNASU; 2614979; -.
DR   EnsemblBacteria; AAF93483; AAF93483; VC_0309.
DR   GeneID; 57739034; -.
DR   KEGG; vch:VC_0309; -.
DR   PATRIC; fig|243277.26.peg.290; -.
DR   eggNOG; COG0043; Bacteria.
DR   HOGENOM; CLU_023348_4_0_6; -.
DR   OMA; SYQQFWG; -.
DR   BioCyc; VCHO:VC0309-MON; -.
DR   UniPathway; UPA00232; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008694; F:3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity; IBA:GO_Central.
DR   GO; GO:0016831; F:carboxy-lyase activity; IBA:GO_Central.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IBA:GO_Central.
DR   InterPro; IPR002830; UbiD.
DR   PANTHER; PTHR30108; PTHR30108; 2.
DR   Pfam; PF01977; UbiD; 2.
DR   TIGRFAMs; TIGR00148; TIGR00148; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Decarboxylase; Lyase; Membrane; Reference proteome;
KW   Ubiquinone biosynthesis.
FT   CHAIN           1..613
FT                   /note="3-octaprenyl-4-hydroxybenzoate carboxy-lyase"
FT                   /id="PRO_0000157366"
FT   REGION          460..584
FT                   /note="Unknown insert"
SQ   SEQUENCE   613 AA;  69242 MW;  92FFA10DDE43287B CRC64;
     MNFKDLRDFL DYLEQRGELK RITHPIDPHY EMTEISDRTL RAKGPALLFE NPLGYDFPVL
     TNLFGTPERV AMGMGRQQVQ ELRDVGQWLA YLKEPEPPRG LKELIEKLPV FKQVLNMPVK
     RLRRAPCQEI VWQGDAVDLD KIPVMSCWPD DVAPLLTWGL TITRGPHKKR QNLGIYRQQK
     IARNKVIMRW LAHRGGALDL RDWMEKHPGE PFPVSVAFGA DPATILGAVT PVPDTLSEYA
     FAGLLRGSRT EVVKSISNDL EVPASAEIVL EGYIDPNEFA DEGPYGDHTG YYNEVERHHV
     FTVTHVTMRN KPIYHSTYTG RPPDEPAVLG VALNEVFVPI LQKQFPEIAD FYLPPEGCSY
     RMAIVTLKKQ YPGHAKRVML GVWSFLRQFM YTKFVIVCDE QVNARDWPQV IAAMVNHMSP
     LRDTLFIEHT PIDSLDFASP VVGLGSKIGL DATAKWPAEL AVSNSDQSDK TTELSLEALK
     ACLSDEADVL DVALPEAAND KLVLLLINKQ EAGQAQQLLQ RVVDKLNGDS PLKFVILCDD
     DVNIHDWNDV IWAMTTRMDP ARDSLRIVGQ DLICFDATNK LPDEVEREWG TPIRKDPKLV
     AKIDSLWDEL GIV