C87A3_ORYSJ
ID C87A3_ORYSJ Reviewed; 514 AA.
AC Q7XU38; Q0JAX4; Q8LPD0;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2005, sequence version 3.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Cytochrome P450 87A3;
DE EC=1.14.-.-;
GN Name=CYP87A3; OrderedLocusNames=Os04g0570000, LOC_Os04g48170;
GN ORFNames=OSJNBa0088I22.16;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND
RP INDUCTION.
RC STRAIN=cv. Nihonmasari;
RX PubMed=14630954; DOI=10.1104/pp.103.022202;
RA Chaban C., Waller F., Furuya M., Nick P.;
RT "Auxin responsiveness of a novel cytochrome p450 in rice coleoptiles.";
RL Plant Physiol. 133:2000-2009(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC {ECO:0000305|PubMed:14630954}. Note=Associated with vesicular
CC membranes. {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in roots and coleoptiles, but not in
CC leaves. {ECO:0000269|PubMed:14630954}.
CC -!- INDUCTION: Transiently induced by auxin and light in dark-grown
CC coleoptiles. {ECO:0000269|PubMed:14630954}.
CC -!- MISCELLANEOUS: Not induced by auxin in the Yin-Yang mutant,
CC characterized by an elevated growth response of the coleoptile to
CC auxin.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAD41584.3; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AJ459255; CAD30852.1; -; mRNA.
DR EMBL; AL607001; CAD41584.3; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008210; BAF15513.1; -; Genomic_DNA.
DR EMBL; AP014960; BAS90563.1; -; Genomic_DNA.
DR RefSeq; XP_015634604.1; XM_015779118.1.
DR AlphaFoldDB; Q7XU38; -.
DR SMR; Q7XU38; -.
DR STRING; 4530.OS04T0570000-00; -.
DR PaxDb; Q7XU38; -.
DR PRIDE; Q7XU38; -.
DR EnsemblPlants; Os04t0570000-00; Os04t0570000-00; Os04g0570000.
DR GeneID; 4336709; -.
DR Gramene; Os04t0570000-00; Os04t0570000-00; Os04g0570000.
DR KEGG; osa:4336709; -.
DR eggNOG; KOG0157; Eukaryota.
DR HOGENOM; CLU_001570_15_5_1; -.
DR InParanoid; Q7XU38; -.
DR OMA; HVQIMEK; -.
DR OrthoDB; 1247045at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR Genevisible; Q7XU38; OS.
DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IBA:GO_Central.
DR GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0016132; P:brassinosteroid biosynthetic process; IBA:GO_Central.
DR GO; GO:0010268; P:brassinosteroid homeostasis; IBA:GO_Central.
DR GO; GO:0016125; P:sterol metabolic process; IBA:GO_Central.
DR Gene3D; 1.10.630.10; -; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; SSF48264; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 2: Evidence at transcript level;
KW Cytoplasmic vesicle; Heme; Iron; Membrane; Metal-binding; Monooxygenase;
KW Oxidoreductase; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..514
FT /note="Cytochrome P450 87A3"
FT /id="PRO_0000052183"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 315..335
FT /note="Helical"
FT /evidence="ECO:0000255"
FT BINDING 463
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000250"
SQ SEQUENCE 514 AA; 57407 MW; 37431B42A4F680B6 CRC64;
MQPYLQLASL RLATTIPLAP RLYDANLLAA SGAAMASSMA YIALLCAALA AVVALLRWAY
RWSHPRSNGR LPPGSLGLPV IGETLQFFAP NPTCDLSPFV KERIKRYGSI FKTSVVGRPV
VVSADPEMNY YVFQQEGKLF ESWYPDTFTE IFGRDNVGSL HGFMYKYLKT LVLRLYGQEN
LKSVLLAETD AACRGSLASW ASQPSVELKE GISTMIFDLT AKKLIGYDPS KPSQVNLRKN
FGAFICGLIS FPLNIPGTAY HECMEGRKNA MKVLRGMMKE RMAEPERPCE DFFDHVIQEL
RREKPLLTET IALDLMFVLL FASFETTALA LTIGVKLLTE NPKVVDALRE EHEAIIRNRK
DPNSGVTWAE YKSMTFTSQV IMEIVRLANI VPGIFRKALQ DVEIKGYTIP AGWGIMVCPP
AVHLNPEIYE DPLAFNPWRW QGKPEITGGT KHFMAFGGGL RFCVGTDLSK VLMATFIHSL
VTKYSWRTVK GGNIVRTPGL SFPDGFHIQL FPKN