ID   UBIJ_SHIFL              Reviewed;         201 AA.
AC   P0ADP8; P27852;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Ubiquinone biosynthesis accessory factor UbiJ {ECO:0000255|HAMAP-Rule:MF_02215};
GN   Name=ubiJ {ECO:0000255|HAMAP-Rule:MF_02215};
GN   Synonyms=yigP {ECO:0000312|EMBL:AAN45347.2, ECO:0000312|EMBL:AAP18851.1};
GN   OrderedLocusNames=SF3912 {ECO:0000312|EMBL:AAN45347.2},
GN   S3842 {ECO:0000312|EMBL:AAP18851.1};
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Required for ubiquinone (coenzyme Q) biosynthesis. Binds
CC       hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain
CC       and is essential for the stability of the Ubi complex. May constitute a
CC       docking platform where Ubi enzymes assemble and access their SCP2-bound
CC       polyprenyl substrates. {ECO:0000255|HAMAP-Rule:MF_02215}.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_02215}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02215}.
CC   -!- SIMILARITY: Belongs to the UbiJ family. {ECO:0000255|HAMAP-
CC       Rule:MF_02215}.
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DR   EMBL; AE005674; AAN45347.2; -; Genomic_DNA.
DR   EMBL; AE014073; AAP18851.1; -; Genomic_DNA.
DR   RefSeq; NP_709640.2; NC_004337.2.
DR   RefSeq; WP_001295259.1; NZ_WPGW01000036.1.
DR   AlphaFoldDB; P0ADP8; -.
DR   SMR; P0ADP8; -.
DR   STRING; 198214.SF3912; -.
DR   EnsemblBacteria; AAN45347; AAN45347; SF3912.
DR   EnsemblBacteria; AAP18851; AAP18851; S3842.
DR   GeneID; 1025101; -.
DR   GeneID; 66672258; -.
DR   KEGG; sfl:SF3912; -.
DR   KEGG; sfx:S3842; -.
DR   PATRIC; fig|198214.7.peg.4612; -.
DR   HOGENOM; CLU_100130_2_0_6; -.
DR   OMA; LELDWEY; -.
DR   OrthoDB; 1959286at2; -.
DR   UniPathway; UPA00232; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0032150; P:ubiquinone biosynthetic process from chorismate; IEA:InterPro.
DR   HAMAP; MF_02215; UbiJ; 1.
DR   InterPro; IPR003033; SCP2_sterol-bd_dom.
DR   InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR   InterPro; IPR038989; UbiJ.
DR   PANTHER; PTHR38693; PTHR38693; 1.
DR   Pfam; PF02036; SCP2; 1.
DR   SUPFAM; SSF55718; SSF55718; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Ubiquinone biosynthesis.
FT   CHAIN           1..201
FT                   /note="Ubiquinone biosynthesis accessory factor UbiJ"
FT                   /id="PRO_0000169669"
FT   DOMAIN          15..112
FT                   /note="SCP2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02215"
SQ   SEQUENCE   201 AA;  22153 MW;  9C64980A59992A2E CRC64;
     MPFKPLVTAG IESLLNTFLY RSPALKTARS RLLGKVLRVE VKGFSTSLIL VFSERQVDVL
     GEWAGDADCT VIAYASVLPK LRDRQQLTAL IRSGELEVQG DIQVVQNFVA LADLAEFDPA
     ELLAPYTGDI AAEGISKAMR GGAKFLHHGI KRQQRYVAEA ITEEWRMAPG PLEVAWFAEE
     TAAVERAVDA LTKRLEKLEA K