UBIT_ECO57
ID UBIT_ECO57 Reviewed; 174 AA.
AC P64601; P45474;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Ubiquinone biosynthesis accessory factor UbiT {ECO:0000255|HAMAP-Rule:MF_02231};
GN Name=ubiT {ECO:0000255|HAMAP-Rule:MF_02231}; Synonyms=yhbT;
GN OrderedLocusNames=Z4518, ECs4038;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: Required for O(2)-independent ubiquinone (coenzyme Q)
CC biosynthesis. Likely functions as an accessory factor.
CC {ECO:0000255|HAMAP-Rule:MF_02231}.
CC -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_02231}.
CC -!- SIMILARITY: Belongs to the UbiT family. {ECO:0000255|HAMAP-
CC Rule:MF_02231}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE005174; AAG58293.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB37461.1; -; Genomic_DNA.
DR PIR; A85979; A85979.
DR PIR; F91133; F91133.
DR RefSeq; NP_312065.1; NC_002695.1.
DR RefSeq; WP_001295552.1; NZ_SWKA01000005.1.
DR AlphaFoldDB; P64601; -.
DR SMR; P64601; -.
DR STRING; 155864.EDL933_4384; -.
DR EnsemblBacteria; AAG58293; AAG58293; Z4518.
DR EnsemblBacteria; BAB37461; BAB37461; ECs_4038.
DR GeneID; 66672942; -.
DR GeneID; 916123; -.
DR KEGG; ece:Z4518; -.
DR KEGG; ecs:ECs_4038; -.
DR PATRIC; fig|386585.9.peg.4217; -.
DR eggNOG; COG3154; Bacteria.
DR HOGENOM; CLU_111894_1_0_6; -.
DR OMA; RDIGLRW; -.
DR UniPathway; UPA00232; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1050.10; -; 1.
DR HAMAP; MF_02231; UbiT; 1.
DR InterPro; IPR039543; POX18/UbiT/NSL-TP1.
DR InterPro; IPR003033; SCP2_sterol-bd_dom.
DR InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR InterPro; IPR016830; UbiT.
DR PANTHER; PTHR10094; PTHR10094; 1.
DR Pfam; PF02036; SCP2; 1.
DR PIRSF; PIRSF025550; UCP025550_lpd_carrier; 1.
DR SUPFAM; SSF55718; SSF55718; 1.
PE 3: Inferred from homology;
KW Reference proteome; Ubiquinone biosynthesis.
FT CHAIN 1..174
FT /note="Ubiquinone biosynthesis accessory factor UbiT"
FT /id="PRO_0000169457"
FT DOMAIN 45..133
FT /note="SCP2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02231"
SQ SEQUENCE 174 AA; 19672 MW; 64AF738130508204 CRC64;
MLDKLRSRIV HLGPSLLSVP VKLTPFALKR QVLEQVLSWQ FRQALDDGEL EFLEGRWLSI
HVRDIDLQWF TSVVNGKLVV SQNAQADVSF SADASDLLMI AARKQDPDTL FFQRRLVIEG
DTELGLYVKN LMDAIELEQM PKALRMMLLQ LADFVEAGMK TAPETKQTSV GEPC
