ID   UBIT_ECOL6              Reviewed;         174 AA.
AC   P64600; P45474;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Ubiquinone biosynthesis accessory factor UbiT {ECO:0000255|HAMAP-Rule:MF_02231};
GN   Name=ubiT {ECO:0000255|HAMAP-Rule:MF_02231}; Synonyms=yhbT;
GN   OrderedLocusNames=c3910;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Required for O(2)-independent ubiquinone (coenzyme Q)
CC       biosynthesis. Likely functions as an accessory factor.
CC       {ECO:0000255|HAMAP-Rule:MF_02231}.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_02231}.
CC   -!- SIMILARITY: Belongs to the UbiT family. {ECO:0000255|HAMAP-
CC       Rule:MF_02231}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN82351.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AE014075; AAN82351.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_001295552.1; NC_004431.1.
DR   AlphaFoldDB; P64600; -.
DR   SMR; P64600; -.
DR   STRING; 199310.c3910; -.
DR   EnsemblBacteria; AAN82351; AAN82351; c3910.
DR   GeneID; 66672942; -.
DR   KEGG; ecc:c3910; -.
DR   eggNOG; COG3154; Bacteria.
DR   HOGENOM; CLU_111894_1_0_6; -.
DR   OMA; RDIGLRW; -.
DR   UniPathway; UPA00232; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.1050.10; -; 1.
DR   HAMAP; MF_02231; UbiT; 1.
DR   InterPro; IPR039543; POX18/UbiT/NSL-TP1.
DR   InterPro; IPR003033; SCP2_sterol-bd_dom.
DR   InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR   InterPro; IPR016830; UbiT.
DR   PANTHER; PTHR10094; PTHR10094; 1.
DR   Pfam; PF02036; SCP2; 1.
DR   PIRSF; PIRSF025550; UCP025550_lpd_carrier; 1.
DR   SUPFAM; SSF55718; SSF55718; 1.
PE   3: Inferred from homology;
KW   Ubiquinone biosynthesis.
FT   CHAIN           1..174
FT                   /note="Ubiquinone biosynthesis accessory factor UbiT"
FT                   /id="PRO_0000169458"
FT   DOMAIN          45..133
FT                   /note="SCP2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02231"
SQ   SEQUENCE   174 AA;  19672 MW;  64AF738130508204 CRC64;
     MLDKLRSRIV HLGPSLLSVP VKLTPFALKR QVLEQVLSWQ FRQALDDGEL EFLEGRWLSI
     HVRDIDLQWF TSVVNGKLVV SQNAQADVSF SADASDLLMI AARKQDPDTL FFQRRLVIEG
     DTELGLYVKN LMDAIELEQM PKALRMMLLQ LADFVEAGMK TAPETKQTSV GEPC