UBN2_BOVIN
ID UBN2_BOVIN Reviewed; 1330 AA.
AC E1B7L7;
DT 11-JAN-2011, integrated into UniProtKB/Swiss-Prot.
DT 02-NOV-2010, sequence version 1.
DT 25-MAY-2022, entry version 52.
DE RecName: Full=Ubinuclein-2;
GN Name=UBN2;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford;
RX PubMed=19390049; DOI=10.1126/science.1169588;
RG The bovine genome sequencing and analysis consortium;
RT "The genome sequence of taurine cattle: a window to ruminant biology and
RT evolution.";
RL Science 324:522-528(2009).
CC -!- SIMILARITY: Belongs to the ubinuclein family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAFC03010356; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAFC03010357; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAFC03080283; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005205927.1; XM_005205870.3.
DR AlphaFoldDB; E1B7L7; -.
DR SMR; E1B7L7; -.
DR STRING; 9913.ENSBTAP00000005889; -.
DR PaxDb; E1B7L7; -.
DR PRIDE; E1B7L7; -.
DR GeneID; 540792; -.
DR CTD; 254048; -.
DR eggNOG; KOG4786; Eukaryota.
DR HOGENOM; CLU_007400_1_0_1; -.
DR InParanoid; E1B7L7; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR InterPro; IPR014840; HRD.
DR InterPro; IPR026943; Ubinuclein-2.
DR InterPro; IPR026947; UBN_middle_dom.
DR PANTHER; PTHR21669:SF10; PTHR21669:SF10; 1.
DR Pfam; PF08729; HUN; 1.
DR Pfam; PF14075; UBN_AB; 1.
PE 3: Inferred from homology;
KW Acetylation; Isopeptide bond; Phosphoprotein; Reference proteome;
KW Ubl conjugation.
FT CHAIN 1..1330
FT /note="Ubinuclein-2"
FT /id="PRO_0000403361"
FT REGION 1..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 574..597
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 672..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 802..833
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 864..913
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 938..988
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1017..1201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1308..1330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..117
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..133
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..298
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..730
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..817
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 938..958
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 971..988
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1028..1046
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1047..1201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 13
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6ZU65"
FT MOD_RES 244
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q6ZU65"
FT MOD_RES 251
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6ZU65"
FT MOD_RES 253
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q6ZU65"
FT MOD_RES 312
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6ZU65"
FT MOD_RES 417
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q80WC1"
FT MOD_RES 420
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q80WC1"
FT MOD_RES 423
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q80WC1"
FT MOD_RES 585
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6ZU65"
FT MOD_RES 1052
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:Q80WC1"
FT MOD_RES 1107
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6ZU65"
FT MOD_RES 1132
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:Q6ZU65"
FT CROSSLNK 273
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q6ZU65"
SQ SEQUENCE 1330 AA; 144390 MW; 783844024CA2DFA5 CRC64;
MAEPRRVAFI SLSPVRRREA EFPGTEREPE YPREPPRLEP QPYREPARTE PPAPREVAPR
SDAQPPPREK PLPQREVSRA EPPMSLQREP PRPEPPPPPL PQLHLQPPPP RESTSRAEPQ
PRPPRETVRL ELVLKDPTDE SCVEFSYPEL LLCGEQRKKP VYTEDPFNDD HQERQEVEML
AKKFEMKYGG KPRKHRRDRL QDLIDIGFGY DETDPFIDNS EAYDELVPAS LTTKYGGFYI
NTGTLQFRQA SDTEEDDTTD NQKHKPPKIP KIKEDDIEMK KRKRKEEGEK EKKPRKKVPK
QLGVMALNSH KSEKKKKRYK DSLSLAAMIR KFQKEKDALK KESNPKTPLN FSTSSLNKPP
SAAVALGNDV SDLNLTSADP DLPIFVSTNE HELFQEAENA LEMLDDFDFD RLLDAASNGS
PLSESGGENG NTTQPTYASQ VMPKVVPTLP EGLPVLLEKR IEDLRVAAKL FDEEGRKKFF
TQDMNNILLD IELQLQELGP VIRSGVYSHL EAFVPCNKET LVKRLKKLHL NVQDDRLREP
LQKLKLAVSN VMPEQLFKYQ EDCQARNQAK CAKFQTDEER EKNGSEEDDE EKPGKRVIGP
RKKFHWDDTI RTLLCNLVEI KLGCYELEPN KSQSAEDYLK SFMETEVKPL WPKGWMQARM
LFKESRSVHN HLTSAPAKKK VIPAPKPKVK ECSPKKDQKT PASSVASVGG PSTSSSTSAV
ASTSSGSTPV QETICLDDSL DEELSFHPPA LDLVSEALAV INNGNKGPPA GSRISMPTAK
PRPGLREEKL ASIMSKLPLA TPKKLDSTQT AHSSSLIAGH TGPVPKKPQD LAHTGISSGL
IAGSSIQNPK VSLEPLPARL LQQGLQRSSQ IHASSSSQTH VSSSSQAQVA ASSHTLGTSE
AQDASPLTQV TKVHQHSAVQ QNYVSPLQAT ISKSQTNPVV KLSNNPQLSC SSPLTKTSDK
PLMYRLPLST PPPGNGSQGS HSLVSRTVPS TTTSTNYLAK AMVSQISTQG FKSPFSMAAS
PKLASSPKPA TSPKPLPSPK PSASPKPSQS AKPSVSTKLI SKSNPTPKPT VSPSSSSPNA
LVAQSSHSSS NNPVHKQPSG MNISRQSPTL NLLPLNRTSG LPSTKNLQAP SKLTNSPSTG
TVGKNSLSGI AMNVPASRGS NLNSSGANRT SLSGGTGSGT QGATKPLSTP HRPSSASGSS
VVAASVQSTA GASLLANASP LTLMTSPLSV TNQNVTPFGM LGGLVPVTMP FQFPLELLGF
GTDTAGVTTT SGSTSAAFHH SLTQNLLKGL QPGAQHAAAL SHAPLPTHVQ QTFNDGGQSK
GDTKLPRKSQ
