ID   C98A2_SOYBN             Reviewed;         509 AA.
AC   O48922;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Cytochrome P450 98A2;
DE            EC=1.14.-.-;
GN   Name=CYP98A2;
OS   Glycine max (Soybean) (Glycine hispida).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC   Glycine subgen. Soja.
OX   NCBI_TaxID=3847;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Siminszky B., Dewey R.E., Corbin F.T.;
RL   Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR   EMBL; AF022458; AAB94587.1; -; mRNA.
DR   PIR; T05937; T05937.
DR   RefSeq; NP_001235563.1; NM_001248634.1.
DR   AlphaFoldDB; O48922; -.
DR   SMR; O48922; -.
DR   STRING; 3847.GLYMA19G30600.1; -.
DR   PRIDE; O48922; -.
DR   EnsemblPlants; KRG95042; KRG95042; GLYMA_19G126000.
DR   GeneID; 606506; -.
DR   Gramene; KRG95042; KRG95042; GLYMA_19G126000.
DR   KEGG; gmx:606506; -.
DR   eggNOG; KOG0156; Eukaryota.
DR   HOGENOM; CLU_001570_4_0_1; -.
DR   InParanoid; O48922; -.
DR   OMA; WHIPHAT; -.
DR   OrthoDB; 702827at2759; -.
DR   Proteomes; UP000008827; Chromosome 19.
DR   Genevisible; O48922; GM.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IBA:GO_Central.
DR   Gene3D; 1.10.630.10; -; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; SSF48264; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   2: Evidence at transcript level;
KW   Heme; Iron; Membrane; Metal-binding; Monooxygenase; Oxidoreductase;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..509
FT                   /note="Cytochrome P450 98A2"
FT                   /id="PRO_0000052198"
FT   TRANSMEM        2..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   BINDING         439
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   509 AA;  57675 MW;  3E3F41FFA3C97D34 CRC64;
     MALLLIIPIS LVTLWLGYTL YQRLRFKLPP GPRPWPVVGN LYDIKPVRFR CFAEWAQSYG
     PIISVWFGST LNVIVSNSEL AKEVLKEHDQ LLADRHRSRS AAKFSRDGKD LIWADYGPHY
     VKVRKVCTLE LFSPKRLEAL RPIREDEVTS MVDSVYNHCT STENLGKGIL LRKHLGVVAF
     NNITRLAFGK RFVNSEGVMD EQGVEFKAIV ENGLKLGASL AMAEHIPWLR WMFPLEEGAF
     AKHGARRDRL TRAIMAEHTE ARKKSGGAKQ HFVDALLTLQ DKYDLSEDTI IGLLWDMITA
     GMDTTAISVE WAMAELIRNP RVQQKVQEEL DRVIGLERVM TEADFSNLPY LQCVTKEAMR
     LHPPTPLMLP HRANANVKVG GYDIPKGSNV HVNVWAVARD PAVWKDPLEF RPERFLEEDV
     DMKGHDFRLL PFGSGRRVCP GAQLGINLAA SMLGHLLHHF CWTPPEGMKP EEIDMGENPG
     LVTYMRTPIQ AVVSPRLPSH LYKRVPAEI