UBP1B_ARATH
ID UBP1B_ARATH Reviewed; 419 AA.
AC Q9LQI9; Q9LNS1;
DT 19-FEB-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 144.
DE RecName: Full=Oligouridylate-binding protein 1B;
DE Short=AtUBP1b;
DE AltName: Full=Polyuridylate-binding protein UBP1B;
DE Short=Poly(U)-binding protein UBP1B;
GN Name=UBP1B; OrderedLocusNames=At1g17370; ORFNames=F1L3.2, F28G4.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF Clones.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP INTERACTION WITH UBA1A AND UBA2A.
RX PubMed=12024044; DOI=10.1128/mcb.22.12.4346-4357.2002;
RA Lambermon M.H., Fu Y., Wieczorek Kirk D.A., Dupasquier M., Filipowicz W.,
RA Lorkovic Z.J.;
RT "UBA1 and UBA2, two proteins that interact with UBP1, a multifunctional
RT effector of pre-mRNA maturation in plants.";
RL Mol. Cell. Biol. 22:4346-4357(2002).
RN [6]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-241, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- FUNCTION: Heterogeneous nuclear ribonucleoprotein (hnRNP)-like protein
CC that acts as a component of the pre-mRNA processing machinery.
CC Functions to facilitate the nuclear maturation of plant pre-mRNAs (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with UBA1A and UBA2A. {ECO:0000269|PubMed:12024044}.
CC -!- INTERACTION:
CC Q9LQI9; Q9SHZ6: UBA1A; NbExp=2; IntAct=EBI-346277, EBI-346271;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9LQI9-1; Sequence=Displayed;
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79492.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC007843; AAF97318.1; -; Genomic_DNA.
DR EMBL; AC022492; AAF79492.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE29579.1; -; Genomic_DNA.
DR EMBL; BT026477; ABH04584.1; -; mRNA.
DR EMBL; AY085705; AAM62923.1; -; mRNA.
DR PIR; C86310; C86310.
DR RefSeq; NP_564018.1; NM_101598.3. [Q9LQI9-1]
DR AlphaFoldDB; Q9LQI9; -.
DR SMR; Q9LQI9; -.
DR IntAct; Q9LQI9; 2.
DR STRING; 3702.AT1G17370.1; -.
DR iPTMnet; Q9LQI9; -.
DR PaxDb; Q9LQI9; -.
DR PRIDE; Q9LQI9; -.
DR ProteomicsDB; 233062; -. [Q9LQI9-1]
DR EnsemblPlants; AT1G17370.1; AT1G17370.1; AT1G17370. [Q9LQI9-1]
DR GeneID; 838309; -.
DR Gramene; AT1G17370.1; AT1G17370.1; AT1G17370. [Q9LQI9-1]
DR KEGG; ath:AT1G17370; -.
DR Araport; AT1G17370; -.
DR TAIR; locus:2018794; AT1G17370.
DR eggNOG; KOG0118; Eukaryota.
DR InParanoid; Q9LQI9; -.
DR OMA; TETRFQS; -.
DR OrthoDB; 1066369at2759; -.
DR PhylomeDB; Q9LQI9; -.
DR PRO; PR:Q9LQI9; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LQI9; baseline and differential.
DR Genevisible; Q9LQI9; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; SSF54928; 3.
DR PROSITE; PS50102; RRM; 3.
PE 1: Evidence at protein level;
KW Alternative splicing; mRNA processing; Nucleus; Phosphoprotein;
KW Reference proteome; Repeat; RNA-binding.
FT CHAIN 1..419
FT /note="Oligouridylate-binding protein 1B"
FT /id="PRO_0000425435"
FT DOMAIN 54..128
FT /note="RRM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 139..217
FT /note="RRM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 260..335
FT /note="RRM 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 217..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 241
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19376835"
SQ SEQUENCE 419 AA; 46049 MW; A43F31C69B30822C CRC64;
MQRLKQQQQQ QQVMMQQALM QQQSLYHPGL LAPPQIEPIP SGNLPPGFDP STCRSVYVGN
IHIQVTEPLL QEVFAGTGPV ESCKLIRKEK SSYGFVHYFD RRSAGLAILS LNGRHLFGQP
IKVNWAYASG QREDTSSHFN IFVGDLSPEV TDAMLFTCFS VYPTCSDARV MWDQKTGRSR
GFGFVSFRNQ QDAQTAIDEI TGKWLGSRQI RCNWATKGAT SGEDKQSSDS KSVVELTSGV
SEDGKDTTNG EAPENNAQYT TVYVGNLAPE VSQVDLHRHF HSLGAGVIEE VRVQRDKGFG
FVRYSTHVEA ALAIQMGNTH SYLSGRQMKC SWGSKPTPAG TASNPLPPPA PAPIPGFSAS
DLLAYERQLA MSKMAGMNPM MHHPQGQHAF KQAAMGATGS NQAIYDGGYQ NAQQLMYYQ
