ID   CA021_MOUSE             Reviewed;         121 AA.
AC   Q8K207;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Uncharacterized protein C1orf21 homolog;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=FVB/N; TISSUE=Mammary tumor;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brain cortex;
RX   PubMed=17114649; DOI=10.1074/mcp.m600046-mcp200;
RA   Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F.,
RA   Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D., Gerrits B.,
RA   Panse C., Schlapbach R., Mansuy I.M.;
RT   "Qualitative and quantitative analyses of protein phosphorylation in naive
RT   and stimulated mouse synaptosomal preparations.";
RL   Mol. Cell. Proteomics 6:283-293(2007).
RN   [3]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-95 AND SER-115, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=19144319; DOI=10.1016/j.immuni.2008.11.006;
RA   Trost M., English L., Lemieux S., Courcelles M., Desjardins M.,
RA   Thibault P.;
RT   "The phagosomal proteome in interferon-gamma-activated macrophages.";
RL   Immunity 30:143-154(2009).
RN   [4]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-95 AND SER-115, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung, Pancreas,
RC   Spleen, and Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
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DR   EMBL; BC034723; AAH34723.1; -; mRNA.
DR   EMBL; BC055912; AAH55912.1; -; mRNA.
DR   CCDS; CCDS35737.1; -.
DR   RefSeq; NP_932107.1; NM_197990.3.
DR   RefSeq; XP_011246371.1; XM_011248069.2.
DR   AlphaFoldDB; Q8K207; -.
DR   SMR; Q8K207; -.
DR   iPTMnet; Q8K207; -.
DR   PhosphoSitePlus; Q8K207; -.
DR   SwissPalm; Q8K207; -.
DR   EPD; Q8K207; -.
DR   jPOST; Q8K207; -.
DR   MaxQB; Q8K207; -.
DR   PaxDb; Q8K207; -.
DR   PRIDE; Q8K207; -.
DR   Antibodypedia; 20606; 50 antibodies from 13 providers.
DR   DNASU; 69399; -.
DR   Ensembl; ENSMUST00000044581; ENSMUSP00000036406; ENSMUSG00000032666.
DR   Ensembl; ENSMUST00000187603; ENSMUSP00000140950; ENSMUSG00000032666.
DR   GeneID; 69399; -.
DR   KEGG; mmu:69399; -.
DR   UCSC; uc007cze.2; mouse.
DR   MGI; MGI:1916649; 1700025G04Rik.
DR   VEuPathDB; HostDB:ENSMUSG00000032666; -.
DR   eggNOG; ENOG502RYJP; Eukaryota.
DR   GeneTree; ENSGT00390000014594; -.
DR   HOGENOM; CLU_136866_0_0_1; -.
DR   InParanoid; Q8K207; -.
DR   OMA; QSRANMH; -.
DR   OrthoDB; 1365051at2759; -.
DR   PhylomeDB; Q8K207; -.
DR   TreeFam; TF333178; -.
DR   BioGRID-ORCS; 69399; 1 hit in 72 CRISPR screens.
DR   PRO; PR:Q8K207; -.
DR   Proteomes; UP000000589; Chromosome 1.
DR   RNAct; Q8K207; protein.
DR   Bgee; ENSMUSG00000032666; Expressed in undifferentiated genital tubercle and 228 other tissues.
DR   ExpressionAtlas; Q8K207; baseline and differential.
DR   Genevisible; Q8K207; MM.
DR   InterPro; IPR027967; DUF4612.
DR   PANTHER; PTHR14974; PTHR14974; 1.
DR   Pfam; PF15389; DUF4612; 1.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..121
FT                   /note="Uncharacterized protein C1orf21 homolog"
FT                   /id="PRO_0000089247"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          60..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        60..76
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         95
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:19144319,
FT                   ECO:0007744|PubMed:21183079"
FT   MOD_RES         115
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:19144319,
FT                   ECO:0007744|PubMed:21183079"
SQ   SEQUENCE   121 AA;  13882 MW;  78520C4326C32AFD CRC64;
     MGCASAKHVA TVQNEEEAQR GKSYQNGDVF GDEYRIKPVE EVKYMKNGAE EEQKIAARNQ
     ENLEKSASSN TRLKTNKEIP GLVHQPRANM HISESQQEFF RMLDEKIEKG RDYCSEEEDI
     T