CA050_MOUSE
ID CA050_MOUSE Reviewed; 199 AA.
AC Q5EBG8;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Uncharacterized protein C1orf50 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Inner ear, and Placenta;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Liver;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Kidney, Liver, Lung, Spleen, and
RC Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
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DR EMBL; AK167445; BAE39531.1; -; mRNA.
DR EMBL; AK158349; BAE34466.1; -; mRNA.
DR EMBL; BC089614; AAH89614.1; -; mRNA.
DR CCDS; CCDS18575.1; -.
DR RefSeq; NP_001012400.1; NM_001012400.2.
DR AlphaFoldDB; Q5EBG8; -.
DR BioGRID; 231002; 1.
DR STRING; 10090.ENSMUSP00000115729; -.
DR iPTMnet; Q5EBG8; -.
DR PhosphoSitePlus; Q5EBG8; -.
DR EPD; Q5EBG8; -.
DR jPOST; Q5EBG8; -.
DR MaxQB; Q5EBG8; -.
DR PaxDb; Q5EBG8; -.
DR PeptideAtlas; Q5EBG8; -.
DR PRIDE; Q5EBG8; -.
DR Antibodypedia; 32249; 181 antibodies from 20 providers.
DR DNASU; 230696; -.
DR Ensembl; ENSMUST00000141112; ENSMUSP00000115729; ENSMUSG00000078584.
DR GeneID; 230696; -.
DR KEGG; mmu:230696; -.
DR UCSC; uc008ulo.2; mouse.
DR MGI; MGI:2140466; AU022252.
DR VEuPathDB; HostDB:ENSMUSG00000078584; -.
DR eggNOG; ENOG502QWKE; Eukaryota.
DR GeneTree; ENSGT00390000003084; -.
DR HOGENOM; CLU_102988_0_1_1; -.
DR InParanoid; Q5EBG8; -.
DR OMA; GCPHDFL; -.
DR OrthoDB; 1483939at2759; -.
DR PhylomeDB; Q5EBG8; -.
DR TreeFam; TF105992; -.
DR BioGRID-ORCS; 230696; 5 hits in 71 CRISPR screens.
DR PRO; PR:Q5EBG8; -.
DR Proteomes; UP000000589; Chromosome 4.
DR RNAct; Q5EBG8; protein.
DR Bgee; ENSMUSG00000078584; Expressed in left lobe of liver and 191 other tissues.
DR Genevisible; Q5EBG8; MM.
DR GO; GO:0042802; F:identical protein binding; ISO:MGI.
DR InterPro; IPR019534; DUF2452.
DR PANTHER; PTHR14553; PTHR14553; 1.
DR Pfam; PF10504; DUF2452; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..199
FT /note="Uncharacterized protein C1orf50 homolog"
FT /id="PRO_0000251190"
FT COILED 71..104
FT /evidence="ECO:0000255"
SQ SEQUENCE 199 AA; 21863 MW; 57BC4A97679AD142 CRC64;
MADPGVPGRY ESGTGNLGVK EAAGPGGALV ELTPTPGGLA LVSPYHTHRV GDPLDLVALA
EQVQKADEFI RANATNKLTV IAEQIQHLQE QARKVLEDAR RDADLHHAAC NMVKKPGNIY
YLYQRESGQQ YFSIISPEEW GTGCPHDFLG AYKLQHDMSW TPYEDVEKQD AKIGMMDKLL
SQPMALPPCT EPTFQGLPH