ID   UBX_MUSDO               Reviewed;         248 AA.
AC   Q25451;
DT   15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Homeotic protein ultrabithorax;
DE   Flags: Fragment;
GN   Name=Ubx;
OS   Musca domestica (House fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Muscidae; Musca.
OX   NCBI_TaxID=7370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=16453766; DOI=10.1002/j.1460-2075.1987.tb02380.x;
RA   Wilde C.D., Akam M.;
RT   "Conserved sequence elements in the 5' region of the Ultrabithorax
RT   transcription unit.";
RL   EMBO J. 6:1393-1401(1987).
CC   -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC       developmental regulatory system that provides cells with specific
CC       positional identities on the anterior-posterior axis. Binds the
CC       consensus region 5'-TTAAT[GT][GA]-3' (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- SIMILARITY: Belongs to the Antp homeobox family. {ECO:0000305}.
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DR   EMBL; X05178; CAA28813.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q25451; -.
DR   STRING; 7370.XP_005178602.1; -.
DR   VEuPathDB; VectorBase:MDOA009747; -.
DR   eggNOG; KOG0489; Eukaryota.
DR   Proteomes; UP000095301; Whole Genome Shotgun Assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   PROSITE; PS00032; ANTENNAPEDIA; 1.
PE   3: Inferred from homology;
KW   Activator; Developmental protein; DNA-binding; Homeobox; Nucleus;
KW   Repressor; Transcription; Transcription regulation.
FT   CHAIN           <1..248
FT                   /note="Homeotic protein ultrabithorax"
FT                   /id="PRO_0000200273"
FT   REGION          116..191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           241..246
FT                   /note="Antp-type hexapeptide"
FT   COMPBIAS        126..143
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
SQ   SEQUENCE   248 AA;  23912 MW;  AD7CE98CC39CCF2E CRC64;
     NSYFEQASGF YGHPHQATGM SMGTAGHHDQ SATAAAAAYR GFPLSLGMTP YTNHHLQRST
     QDSPYDASIT AACNKIYGDG NAYKQDCLNI KSDTINGYKD IWNTTANGGG AGGGGGTGGG
     GGGSAGSANG ANNTANGQNT SGGGGAGGGG GMPVRPSACT PDSRVGGYLD TSGGSPVSHR
     GGSAGVVGGA GTGVGQSGQS ANVGGAGGVG GATAWNANCT ISGAAAAQTA SSLHQASNHT
     FYPWMAIA