CA054_MOUSE
ID CA054_MOUSE Reviewed; 148 AA.
AC Q8R2K8; Q8K3T8;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 2.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Uncharacterized protein C1orf54 homolog;
DE AltName: Full=Protein L259;
DE Flags: Precursor;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RA Han S.H., Choi I.P.;
RL Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=C57BL/6J; TISSUE=Mammary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8R2K8-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8R2K8-2; Sequence=VSP_020746;
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DR EMBL; AF534879; AAN03482.1; -; mRNA.
DR EMBL; BC028528; AAH28528.1; -; mRNA.
DR CCDS; CCDS50998.1; -. [Q8R2K8-1]
DR CCDS; CCDS84656.1; -. [Q8R2K8-2]
DR RefSeq; NP_001333443.1; NM_001346514.1. [Q8R2K8-2]
DR RefSeq; NP_705733.2; NM_153513.3. [Q8R2K8-1]
DR AlphaFoldDB; Q8R2K8; -.
DR STRING; 10090.ENSMUSP00000102749; -.
DR GlyGen; Q8R2K8; 1 site.
DR PhosphoSitePlus; Q8R2K8; -.
DR PaxDb; Q8R2K8; -.
DR PRIDE; Q8R2K8; -.
DR Antibodypedia; 20279; 71 antibodies from 12 providers.
DR DNASU; 229600; -.
DR Ensembl; ENSMUST00000036360; ENSMUSP00000046810; ENSMUSG00000038543. [Q8R2K8-2]
DR Ensembl; ENSMUST00000090476; ENSMUSP00000102749; ENSMUSG00000038543. [Q8R2K8-1]
DR Ensembl; ENSMUST00000171519; ENSMUSP00000127666; ENSMUSG00000038543. [Q8R2K8-1]
DR GeneID; 229600; -.
DR KEGG; mmu:229600; -.
DR UCSC; uc008qln.3; mouse. [Q8R2K8-2]
DR UCSC; uc008qlo.2; mouse. [Q8R2K8-1]
DR MGI; MGI:2385885; BC028528.
DR VEuPathDB; HostDB:ENSMUSG00000038543; -.
DR eggNOG; ENOG502RVU7; Eukaryota.
DR GeneTree; ENSGT00390000003103; -.
DR HOGENOM; CLU_130480_0_0_1; -.
DR InParanoid; Q8R2K8; -.
DR OMA; WALIQGG; -.
DR OrthoDB; 1538878at2759; -.
DR PhylomeDB; Q8R2K8; -.
DR TreeFam; TF336874; -.
DR BioGRID-ORCS; 229600; 4 hits in 71 CRISPR screens.
DR PRO; PR:Q8R2K8; -.
DR Proteomes; UP000000589; Chromosome 3.
DR RNAct; Q8R2K8; protein.
DR Bgee; ENSMUSG00000038543; Expressed in right lung lobe and 190 other tissues.
DR Genevisible; Q8R2K8; MM.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR027957; DUF4634.
DR PANTHER; PTHR37870; PTHR37870; 1.
DR Pfam; PF15465; DUF4634; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Glycoprotein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..16
FT /evidence="ECO:0000255"
FT CHAIN 17..148
FT /note="Uncharacterized protein C1orf54 homolog"
FT /id="PRO_0000251201"
FT REGION 91..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 50
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT VAR_SEQ 117
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_020746"
SQ SEQUENCE 148 AA; 16823 MW; F52EC31DB4E9F5EC CRC64;
MDVLFIALLV APLILGQEYD HEEQLEEGDY YQVAYYYYTV TPNYDDFSVN FTVDYSVFES
EDRLNRLNKE VTTTEAVETT ASSYSLHTEL MDPQNPVTTK PVTTEPVTTE PVTTEPQSPN
QNDAMSTLQS PVSCFLLWTL LQGGVHFM
