ID   UCP3_SCHPO              Reviewed;         601 AA.
AC   O74345;
DT   29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 126.
DE   RecName: Full=UBA domain-containing protein 3;
GN   Name=ucp3; Synonyms=soc2; ORFNames=SPBC21D10.05c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=11584278; DOI=10.1038/ncb1001-939;
RA   Wilkinson C.R.M., Seeger M., Hartmann-Petersen R., Stone M., Wallace M.,
RA   Semple C., Gordon C.;
RT   "Proteins containing the UBA domain are able to bind to multi-ubiquitin
RT   chains.";
RL   Nat. Cell Biol. 3:939-943(2001).
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DR   EMBL; CU329671; CAA20761.1; -; Genomic_DNA.
DR   PIR; T11677; T11677.
DR   RefSeq; NP_596008.1; NM_001021916.2.
DR   AlphaFoldDB; O74345; -.
DR   SMR; O74345; -.
DR   BioGRID; 277232; 3.
DR   STRING; 4896.SPBC21D10.05c.1; -.
DR   iPTMnet; O74345; -.
DR   MaxQB; O74345; -.
DR   PaxDb; O74345; -.
DR   EnsemblFungi; SPBC21D10.05c.1; SPBC21D10.05c.1:pep; SPBC21D10.05c.
DR   GeneID; 2540709; -.
DR   KEGG; spo:SPBC21D10.05c; -.
DR   PomBase; SPBC21D10.05c; ucp3.
DR   VEuPathDB; FungiDB:SPBC21D10.05c; -.
DR   eggNOG; KOG0703; Eukaryota.
DR   HOGENOM; CLU_421007_0_0_1; -.
DR   InParanoid; O74345; -.
DR   OMA; FEQMMAM; -.
DR   PhylomeDB; O74345; -.
DR   PRO; PR:O74345; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0030479; C:actin cortical patch; ISO:PomBase.
DR   GO; GO:0032153; C:cell division site; HDA:PomBase.
DR   GO; GO:0071944; C:cell periphery; IDA:PomBase.
DR   GO; GO:0051286; C:cell tip; HDA:PomBase.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005096; F:GTPase activator activity; ISM:PomBase.
DR   GO; GO:0031593; F:polyubiquitin modification-dependent protein binding; TAS:PomBase.
DR   GO; GO:0043130; F:ubiquitin binding; ISM:PomBase.
DR   GO; GO:0051523; P:cell growth mode switching, monopolar to bipolar; IMP:PomBase.
DR   GO; GO:0006897; P:endocytosis; ISO:PomBase.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IBA:GO_Central.
DR   Gene3D; 1.10.220.150; -; 1.
DR   InterPro; IPR037278; ARFGAP/RecO.
DR   InterPro; IPR001164; ArfGAP_dom.
DR   InterPro; IPR038508; ArfGAP_dom_sf.
DR   InterPro; IPR015940; UBA.
DR   InterPro; IPR009060; UBA-like_sf.
DR   Pfam; PF01412; ArfGap; 1.
DR   Pfam; PF00627; UBA; 1.
DR   PRINTS; PR00405; REVINTRACTNG.
DR   SMART; SM00105; ArfGap; 1.
DR   SMART; SM00165; UBA; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   SUPFAM; SSF57863; SSF57863; 1.
DR   PROSITE; PS50115; ARFGAP; 1.
DR   PROSITE; PS50030; UBA; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..601
FT                   /note="UBA domain-containing protein 3"
FT                   /id="PRO_0000065714"
FT   DOMAIN          7..129
FT                   /note="Arf-GAP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00288"
FT   DOMAIN          157..197
FT                   /note="UBA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00212"
FT   REGION          123..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          289..310
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..158
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   601 AA;  65542 MW;  D84707E1E43A04F7 CRC64;
     MSGRRNETAI RELVQSVSGN NLCADCSTRG VQWASWNLGI FLCLRCATIH RKLGTHVSKV
     KSISLDEWSN DQIEKMKHWG NINANRYWNP NPLSHPLPTN ALSDEHVMEK YIRDKYERKL
     FLDENHSTNS KPPSLPPRTK SSSQSSPMAS TSTSKSRYAD SLSTLHDMGF SDDSVNTHAL
     EETNGDVTRA IEKIVQHGSS KPQKPSTLTS TKSTIKLVSA RLKKRNKNLS VHFEDGTKPG
     DAYEVTGDTR AASPTLNPFE QMMAMTNQGM SVSPGVETTS SPFFTAPVEP NQPLQPLRPS
     MTGPVPSSMG SEATLNMPST YGIDSNLYTN SNSSSIVQNP LQPARTGPAA INYNYTTNYS
     VSSPSVTNPF FDVGSSTQNA SLMGSTGYPS SANNVYYENS YQGVGTSMSD NYQLPDMSKL
     SLNEQPAAPS NSNSQYMNTS MPTLDSTNMY GQSNQDPYSM SNGVYGSNYS AQPSTMQMQA
     TGIAPPQPNM SMQMPMSMQS TGYQMPMENT WVDYNGMSQQ GNGMQPATMN YSNSMGYDTN
     VPADNGYYQQ GYGNVMMPPD ASYTGTGSYV QPMNQPSGGM GAPADSSKAD SYIQRIMQGK
     Q