UCP6_SCHPO
ID UCP6_SCHPO Reviewed; 612 AA.
AC Q10187;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=UBA domain-containing protein 6;
GN Name=ucp6; ORFNames=SPAC3F10.13;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP IDENTIFICATION.
RX PubMed=11584278; DOI=10.1038/ncb1001-939;
RA Wilkinson C.R.M., Seeger M., Hartmann-Petersen R., Stone M., Wallace M.,
RA Semple C., Gordon C.;
RT "Proteins containing the UBA domain are able to bind to multi-ubiquitin
RT chains.";
RL Nat. Cell Biol. 3:939-943(2001).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-595, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329670; CAA93311.1; -; Genomic_DNA.
DR PIR; T38714; T38714.
DR RefSeq; NP_593945.1; NM_001019373.2.
DR AlphaFoldDB; Q10187; -.
DR SMR; Q10187; -.
DR BioGRID; 279478; 18.
DR STRING; 4896.SPAC3F10.13.1; -.
DR iPTMnet; Q10187; -.
DR MaxQB; Q10187; -.
DR PaxDb; Q10187; -.
DR PRIDE; Q10187; -.
DR EnsemblFungi; SPAC3F10.13.1; SPAC3F10.13.1:pep; SPAC3F10.13.
DR GeneID; 2543043; -.
DR KEGG; spo:SPAC3F10.13; -.
DR PomBase; SPAC3F10.13; ucp6.
DR VEuPathDB; FungiDB:SPAC3F10.13; -.
DR HOGENOM; CLU_441570_0_0_1; -.
DR InParanoid; Q10187; -.
DR OMA; NSACEFP; -.
DR PRO; PR:Q10187; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0031593; F:polyubiquitin modification-dependent protein binding; TAS:PomBase.
DR GO; GO:0043130; F:ubiquitin binding; TAS:PomBase.
DR GO; GO:0016579; P:protein deubiquitination; ISO:PomBase.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF46934; SSF46934; 1.
DR PROSITE; PS50030; UBA; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..612
FT /note="UBA domain-containing protein 6"
FT /id="PRO_0000065715"
FT DOMAIN 3..42
FT /note="UBA"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00212"
FT MOD_RES 595
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 612 AA; 68721 MW; 3FBFDF3808F554CD CRC64;
MEDLDTKIKT LKNMGVSESD AKDSLERCGY DVESAAEFIF SGQLEKSRLV PIMSSTSIAS
SLPSYQDTFF LPSPRKRRRL PGRIGTVLKP SALFPAIAPF LFVVFEIPVA LNTFVHATCK
GLLFAEDNAS FHRPFTDVSA HLSSSSLSKY NHHSNHRLAS PGWWYGEDSC ISQSLDPRSV
MQVQTIRAFE FLFSSHRLYL DTVHITAALS QVLAGLGNTN TSMSDGDCIA AFLSSYFSPP
NAEFDSTFCS TLSSLTNSEK PTYIFNFKPN STPDLRLSIE SCLDLLLHPP SSAQKNWSWI
KHVGKVFCCS LPGNNASGTP RFLLTPKIDL SKCIIENRDE MLRRYQLETV YRKTLLEWED
LYKRLTGVTL TDKDIGELLT DGQQFLEKRN PALSSHLQLL KETLQTKIST LISNTNATQH
KLSTLYRGMQ NKCTRRLLAV IIEPSIIYIC LKNSAVQSNR NVSPSANHNE QWYLVRFTTS
ATISQDSPPC IVEPVTFEEV DLEFEKHISY HNRLLIYVDD DCEASTRTVI PTSVKNFIAE
DNEYFDDELA GIIHSPTVST RSSRSSDVSE YDLEDQGGLQ LTVPHINTDV QCHRSRNSAC
EFPESMHVEH SG
