ID   UCPA_SALTI              Reviewed;         263 AA.
AC   P0A2D2; P37441;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Oxidoreductase UcpA;
DE            EC=1.-.-.-;
GN   Name=ucpA; OrderedLocusNames=STY2682, t0413;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; AL513382; CAD07676.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO68131.1; -; Genomic_DNA.
DR   RefSeq; NP_456980.1; NC_003198.1.
DR   RefSeq; WP_000517460.1; NZ_WSUR01000025.1.
DR   AlphaFoldDB; P0A2D2; -.
DR   SMR; P0A2D2; -.
DR   STRING; 220341.16503662; -.
DR   EnsemblBacteria; AAO68131; AAO68131; t0413.
DR   KEGG; stt:t0413; -.
DR   KEGG; sty:STY2682; -.
DR   PATRIC; fig|220341.7.peg.2719; -.
DR   eggNOG; COG1028; Bacteria.
DR   HOGENOM; CLU_010194_1_0_6; -.
DR   OMA; NISSMWG; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..263
FT                   /note="Oxidoreductase UcpA"
FT                   /id="PRO_0000054803"
FT   ACT_SITE        155
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   BINDING         10..32
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
FT   BINDING         141
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   263 AA;  27870 MW;  81B26CAD9B4D534E CRC64;
     MGKLTGKTAL ITGASQGIGE GIARVFARHG ANLILLDISD EIEKLADELG GRGHRCTAVK
     ADVRDFASVQ AAVARAKETE GRIDILVNNA GVCRLGNFLD MSEEDRDFHI DINIKGVWNV
     TKAVLPEMIK RKDGRIVMMS SVTGDMVADP GETAYALSKA AIVGLTKSLA VEYAQSGIRV
     NAICPGYVRT PMAESIARQS NPDDPESVLT EMAKAIPLRR LADPLEVGEL AAFLASDESS
     YLTGTQNVID GGSTLPESVS VGV