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UCPA_SALTY
ID   UCPA_SALTY              Reviewed;         263 AA.
AC   P0A2D1; P37441;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Oxidoreductase UcpA;
DE            EC=1.-.-.-;
GN   Name=ucpA; OrderedLocusNames=STM2445;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 204-263.
RX   PubMed=1909324; DOI=10.1128/jb.173.18.5876-5886.1991;
RA   Hryniewicz M.M., Kredich N.M.;
RT   "The cysP promoter of Salmonella typhimurium: characterization of two
RT   binding sites for CysB protein, studies of in vivo transcription
RT   initiation, and demonstration of the anti-inducer effects of thiosulfate.";
RL   J. Bacteriol. 173:5876-5886(1991).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; AE006468; AAL21339.1; -; Genomic_DNA.
DR   PIR; A38121; A38121.
DR   RefSeq; NP_461380.1; NC_003197.2.
DR   RefSeq; WP_000517460.1; NC_003197.2.
DR   AlphaFoldDB; P0A2D1; -.
DR   SMR; P0A2D1; -.
DR   STRING; 99287.STM2445; -.
DR   PaxDb; P0A2D1; -.
DR   PRIDE; P0A2D1; -.
DR   EnsemblBacteria; AAL21339; AAL21339; STM2445.
DR   GeneID; 1253967; -.
DR   KEGG; stm:STM2445; -.
DR   PATRIC; fig|99287.12.peg.2583; -.
DR   HOGENOM; CLU_010194_1_0_6; -.
DR   OMA; NISSMWG; -.
DR   PhylomeDB; P0A2D1; -.
DR   BioCyc; SENT99287:STM2445-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..263
FT                   /note="Oxidoreductase UcpA"
FT                   /id="PRO_0000054804"
FT   ACT_SITE        155
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   BINDING         10..32
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
FT   BINDING         141
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        218
FT                   /note="L -> M (in Ref. 2)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        258
FT                   /note="S -> T (in Ref. 2)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        263
FT                   /note="V -> I (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   263 AA;  27870 MW;  81B26CAD9B4D534E CRC64;
     MGKLTGKTAL ITGASQGIGE GIARVFARHG ANLILLDISD EIEKLADELG GRGHRCTAVK
     ADVRDFASVQ AAVARAKETE GRIDILVNNA GVCRLGNFLD MSEEDRDFHI DINIKGVWNV
     TKAVLPEMIK RKDGRIVMMS SVTGDMVADP GETAYALSKA AIVGLTKSLA VEYAQSGIRV
     NAICPGYVRT PMAESIARQS NPDDPESVLT EMAKAIPLRR LADPLEVGEL AAFLASDESS
     YLTGTQNVID GGSTLPESVS VGV
 
 
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