ID   UDPE_GVLO               Reviewed;         460 AA.
AC   Q98166;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   23-FEB-2022, entry version 58.
DE   RecName: Full=Ecdysteroid UDP-glucosyltransferase;
DE            EC=2.4.1.-;
DE   Flags: Precursor;
GN   Name=EGT;
OS   Lacanobia oleracea granulosis virus (LoGV) (Lacanobia oleracea
OS   granulovirus).
OC   Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Betabaculovirus.
OX   NCBI_TaxID=52412;
OH   NCBI_TaxID=79499; Lacanobia oleracea.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Scottish / LOGV-S1;
RX   PubMed=9472627; DOI=10.1099/0022-1317-79-2-405;
RA   Smith I., Goodale C.;
RT   "Sequence and in vivo transcription of the Lacanobia oleracea granulovirus
RT   egt.";
RL   J. Gen. Virol. 79:405-413(1998).
CC   -!- FUNCTION: Catalyzes the transfer of glucose from UDP-glucose to
CC       ecdysteroids which are insect molting hormones. Expression of egt
CC       interferes with normal insect development and block molting (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC       {ECO:0000305}.
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DR   EMBL; Y08294; CAA69602.1; -; Genomic_DNA.
DR   SMR; Q98166; -.
DR   CAZy; GT1; Glycosyltransferase Family 1.
DR   Proteomes; UP000242554; Genome.
DR   GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR   CDD; cd03784; GT1_Gtf-like; 1.
DR   InterPro; IPR016224; Ecdysteroid_UDP-Glc_Trfase.
DR   InterPro; IPR002213; UDP_glucos_trans.
DR   InterPro; IPR035595; UDP_glycos_trans_CS.
DR   Pfam; PF00201; UDPGT; 1.
DR   PIRSF; PIRSF000476; Ecdystd_UDP_glucosyltfrase; 1.
DR   PROSITE; PS00375; UDPGT; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase; Signal; Transferase.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..460
FT                   /note="Ecdysteroid UDP-glucosyltransferase"
FT                   /id="PRO_0000036056"
SQ   SEQUENCE   460 AA;  52732 MW;  298CA74C5D939A9C CRC64;
     MFISILLLAL AVERILCANI LCVFPTPAYS HQSVFSAYID KLSWAGHNVT VITPMPRAVD
     HVHQVVSSLS VHYFNNLIKN STMIKKRGVV ADETTVTKEN YMGLINLVAH EIKSPNVTRL
     LRNKGNKFDL IVCEAYVSYI LVFGAIYDAP VIQFSSGYAI PENFETVGGE VARNHIKHPN
     IWRSDFSKSN FEQLMTENYL KNEWALLEKE QENMLKRDFG YHHDMCQLKS RVLMLFINVP
     AVFDNNRDVS NNIQYLGGIH LKKPRTVRDS RLLSFMEKHH IIVYASFGSG IDVLNMDANL
     IAEFVRVFNS IPYAVLWKVD SSIHLKHNIS SNVHTQSWFP QRDVLNHPHI KVFITQGGVQ
     STDEAVNSGV PMIGIPIMGD QFYNVRRYTE LGIGEKVNIL RLEEEGLDRK IKNLVHNKSY
     ELNIKRLNLF ISDTPVKPLR KALWFTNYVL RNKDAIDKFK