ID   UDP_LACRH               Reviewed;          23 AA.
AC   P19662;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Uridine phosphorylase;
DE            EC=2.4.2.3;
DE   AltName: Full=UDRPase;
DE   Flags: Fragment;
GN   Name=udp;
OS   Lacticaseibacillus rhamnosus (Lactobacillus rhamnosus).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lacticaseibacillus.
OX   NCBI_TaxID=47715;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=ATCC 7469 / DSM 20021 / JCM 1136 / CCUG 21452 / KCTC 1046 / NCDO 243
RC   / NCIMB 6375 / NCTC 12953;
RX   PubMed=2119230; DOI=10.1016/0167-4838(90)90089-x;
RA   Avraham Y., Grossowicz N., Yashphe J.;
RT   "Purification and characterization of uridine and thymidine phosphorylase
RT   from Lactobacillus casei.";
RL   Biochim. Biophys. Acta 1040:287-293(1990).
CC   -!- FUNCTION: The enzymes which catalyze the reversible phosphorolysis of
CC       pyrimidine nucleosides are involved in the degradation of these
CC       compounds and in their utilization as carbon and energy sources, or in
CC       the rescue of pyrimidine bases for nucleotide synthesis.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=phosphate + uridine = alpha-D-ribose 1-phosphate + uracil;
CC         Xref=Rhea:RHEA:24388, ChEBI:CHEBI:16704, ChEBI:CHEBI:17568,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:57720; EC=2.4.2.3;
CC   -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via salvage pathway;
CC       uracil from uridine (phosphorylase route): step 1/1.
CC   -!- SUBUNIT: Homotetramer.
CC   -!- SIMILARITY: Belongs to the PNP/UDP phosphorylase family. {ECO:0000305}.
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DR   PIR; S11383; S11383.
DR   AlphaFoldDB; P19662; -.
DR   STRING; 568703.LGG_01998; -.
DR   eggNOG; COG1898; Bacteria.
DR   UniPathway; UPA00574; UER00633.
DR   GO; GO:0004850; F:uridine phosphorylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044206; P:UMP salvage; IEA:UniProtKB-UniPathway.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Glycosyltransferase; Transferase.
FT   CHAIN           1..>23
FT                   /note="Uridine phosphorylase"
FT                   /id="PRO_0000063189"
FT   UNSURE          1
FT                   /note="R or S"
FT   UNSURE          7
FT                   /note="E or T"
FT   NON_TER         23
SQ   SEQUENCE   23 AA;  2630 MW;  918B2E2F32F35A17 CRC64;
     RLKVIPEKLK DVKLVCTDVF GDN