ID   UEHB_RUEPO              Reviewed;         188 AA.
AC   Q5LUA8;
DT   20-JAN-2016, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Ectoine/5-hydroxyectoine TRAP transporter small permease protein UehB {ECO:0000305};
DE   AltName: Full=Uptake of ectoine and hydroxyectoine protein B {ECO:0000305};
GN   Name=uehB {ECO:0000303|PubMed:19362561};
GN   OrderedLocusNames=SPO1146 {ECO:0000312|EMBL:AAV94446.1};
OS   Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter
OS   pomeroyi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Ruegeria.
OX   NCBI_TaxID=246200;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3;
RX   PubMed=15602564; DOI=10.1038/nature03170;
RA   Moran M.A., Buchan A., Gonzalez J.M., Heidelberg J.F., Whitman W.B.,
RA   Kiene R.P., Henriksen J.R., King G.M., Belas R., Fuqua C., Brinkac L.M.,
RA   Lewis M., Johri S., Weaver B., Pai G., Eisen J.A., Rahe E., Sheldon W.M.,
RA   Ye W., Miller T.R., Carlton J., Rasko D.A., Paulsen I.T., Ren Q.,
RA   Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Madupu R.,
RA   Nelson W.C., Sullivan S.A., Rosovitz M.J., Haft D.H., Selengut J., Ward N.;
RT   "Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine
RT   environment.";
RL   Nature 432:910-913(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3;
RX   PubMed=25780504; DOI=10.1186/1944-3277-9-11;
RA   Rivers A.R., Smith C.B., Moran M.A.;
RT   "An updated genome annotation for the model marine bacterium Ruegeria
RT   pomeroyi DSS-3.";
RL   Stand. Genomic Sci. 9:11-11(2014).
RN   [3]
RP   PROBABLE FUNCTION, AND SUBUNIT.
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3;
RX   PubMed=19362561; DOI=10.1016/j.jmb.2009.03.077;
RA   Lecher J., Pittelkow M., Zobel S., Bursy J., Bonig T., Smits S.H.,
RA   Schmitt L., Bremer E.;
RT   "The crystal structure of UehA in complex with ectoine-A comparison with
RT   other TRAP-T binding proteins.";
RL   J. Mol. Biol. 389:58-73(2009).
CC   -!- FUNCTION: Part of the tripartite ATP-independent periplasmic (TRAP)
CC       transport system UehABC, which imports both ectoine and 5-
CC       hydroxyectoine as nutrients, and not as osmoprotectants.
CC       {ECO:0000305|PubMed:19362561}.
CC   -!- SUBUNIT: The complex comprises the extracytoplasmic solute receptor
CC       protein UehA, and the two transmembrane proteins UehB and UehC.
CC       {ECO:0000305|PubMed:19362561}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000255}.
CC   -!- MISCELLANEOUS: Transport is enhanced in cells that are grown in the
CC       presence of ectoine, but not by high-salinity media.
CC       {ECO:0000269|PubMed:19362561}.
CC   -!- SIMILARITY: Belongs to the TRAP transporter small permease family.
CC       {ECO:0000305}.
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DR   EMBL; CP000031; AAV94446.1; -; Genomic_DNA.
DR   RefSeq; WP_011046893.1; NC_003911.12.
DR   AlphaFoldDB; Q5LUA8; -.
DR   STRING; 246200.SPO1146; -.
DR   EnsemblBacteria; AAV94446; AAV94446; SPO1146.
DR   KEGG; sil:SPO1146; -.
DR   eggNOG; COG3090; Bacteria.
DR   HOGENOM; CLU_086356_3_7_5; -.
DR   OMA; RHIRMSA; -.
DR   OrthoDB; 1947990at2; -.
DR   Proteomes; UP000001023; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007387; TRAP_DctQ.
DR   PANTHER; PTHR35011; PTHR35011; 1.
DR   Pfam; PF04290; DctQ; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..188
FT                   /note="Ectoine/5-hydroxyectoine TRAP transporter small
FT                   permease protein UehB"
FT                   /id="PRO_0000435356"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   188 AA;  20729 MW;  FBD5899E1BDF266B CRC64;
     MQQTHESALP GFLGMLDSAI SRIESFLLAM GVLLMAANTV ANVVGRFVLG NSIFFSEELN
     RILIILITFA GISYAARNAR HIRMSAVYDL LPARLRKGMM VVISVVTAAF MFLLCYYAAK
     YIGSQASRGR VLPALQIPVW VILIWVPAGF FMTGAQYLLT AVRNLTSSGI YLSTHVQEGY
     EDAEEIEI