ID   UFC1_CAEBR              Reviewed;         162 AA.
AC   A8XAF4;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Ubiquitin-fold modifier-conjugating enzyme 1;
DE   AltName: Full=Ufm1-conjugating enzyme 1;
GN   Name=ufc-1 {ECO:0000312|WormBase:CBG10119};
GN   ORFNames=CBG10119 {ECO:0000312|WormBase:CBG10119};
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: E2-like enzyme which forms an intermediate with ufm-1. The
CC       intermediate is formed via a thioester linkage.
CC       {ECO:0000250|UniProtKB:Q03598, ECO:0000250|UniProtKB:Q9Y3C8}.
CC   -!- SUBUNIT: Interacts with uba-5. {ECO:0000250|UniProtKB:Q03598}.
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UFC1
CC       subfamily. {ECO:0000305}.
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DR   EMBL; HE601459; CAP29622.1; -; Genomic_DNA.
DR   RefSeq; XP_002641773.1; XM_002641727.1.
DR   AlphaFoldDB; A8XAF4; -.
DR   SMR; A8XAF4; -.
DR   STRING; 6238.CBG10119; -.
DR   GeneID; 8583767; -.
DR   KEGG; cbr:CBG_10119; -.
DR   CTD; 8583767; -.
DR   WormBase; CBG10119; CBP46807; WBGene00031590; Cbr-ufc-1.
DR   eggNOG; KOG3357; Eukaryota.
DR   HOGENOM; CLU_101170_0_0_1; -.
DR   InParanoid; A8XAF4; -.
DR   OMA; IKYVQNN; -.
DR   OrthoDB; 1339876at2759; -.
DR   Proteomes; UP000008549; Chromosome III.
DR   GO; GO:0061657; F:UFM1 conjugating enzyme activity; IEA:InterPro.
DR   GO; GO:0071568; F:UFM1 transferase activity; IBA:GO_Central.
DR   GO; GO:1990592; P:protein K69-linked ufmylation; IBA:GO_Central.
DR   Gene3D; 3.10.110.10; -; 1.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   InterPro; IPR014806; Ufc1.
DR   PANTHER; PTHR12921; PTHR12921; 1.
DR   Pfam; PF08694; UFC1; 1.
DR   PIRSF; PIRSF008716; DUF1782; 1.
DR   SUPFAM; SSF54495; SSF54495; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ubl conjugation pathway.
FT   CHAIN           1..162
FT                   /note="Ubiquitin-fold modifier-conjugating enzyme 1"
FT                   /id="PRO_0000391963"
FT   ACT_SITE        115
FT                   /note="Glycyl thioester intermediate"
FT                   /evidence="ECO:0000250|UniProtKB:Q9Y3C8"
SQ   SEQUENCE   162 AA;  18464 MW;  7A98FFA3AFD52D44 CRC64;
     MDETTKSSLK AIPLCKTKAG PRDGDLWMER LKAKYEAIIA AVQNNKTSDR DWFKLEANER
     GTKWFGKCWY FHNMVKYEFD VEFDIPITYP VTAPEIALPE LDGKTAKMYR GGKICLSEHF
     KPLWARNTPK FGIAHAFALG LGPWMAVEIP DLIEKGIIQP KA