ID   UFC1_TRIAD              Reviewed;         168 AA.
AC   B3RTL9;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Ubiquitin-fold modifier-conjugating enzyme 1;
DE   AltName: Full=Ufm1-conjugating enzyme 1;
GN   ORFNames=TRIADDRAFT_35934;
OS   Trichoplax adhaerens (Trichoplax reptans).
OC   Eukaryota; Metazoa; Placozoa; Trichoplacidae; Trichoplax.
OX   NCBI_TaxID=10228;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Grell-BS-1999;
RX   PubMed=18719581; DOI=10.1038/nature07191;
RA   Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA   Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA   Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA   Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA   Rokhsar D.S.;
RT   "The Trichoplax genome and the nature of placozoans.";
RL   Nature 454:955-960(2008).
CC   -!- FUNCTION: E2-like enzyme which forms an intermediate with UFM1 via a
CC       thioester linkage. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UFC1
CC       subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS985244; EDV26152.1; -; Genomic_DNA.
DR   RefSeq; XP_002112185.1; XM_002112149.1.
DR   AlphaFoldDB; B3RTL9; -.
DR   SMR; B3RTL9; -.
DR   STRING; 10228.TriadP35934; -.
DR   EnsemblMetazoa; TriadT35934; TriadP35934; TriadG35934.
DR   GeneID; 6753398; -.
DR   KEGG; tad:TRIADDRAFT_35934; -.
DR   CTD; 6753398; -.
DR   eggNOG; KOG3357; Eukaryota.
DR   HOGENOM; CLU_101170_0_0_1; -.
DR   InParanoid; B3RTL9; -.
DR   OMA; IKYVQNN; -.
DR   OrthoDB; 1339876at2759; -.
DR   PhylomeDB; B3RTL9; -.
DR   Proteomes; UP000009022; Unassembled WGS sequence.
DR   GO; GO:0061657; F:UFM1 conjugating enzyme activity; IEA:InterPro.
DR   GO; GO:0071568; F:UFM1 transferase activity; IBA:GO_Central.
DR   GO; GO:1990592; P:protein K69-linked ufmylation; IBA:GO_Central.
DR   Gene3D; 3.10.110.10; -; 1.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   InterPro; IPR014806; Ufc1.
DR   PANTHER; PTHR12921; PTHR12921; 1.
DR   Pfam; PF08694; UFC1; 1.
DR   PIRSF; PIRSF008716; DUF1782; 1.
DR   SUPFAM; SSF54495; SSF54495; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ubl conjugation pathway.
FT   CHAIN           1..168
FT                   /note="Ubiquitin-fold modifier-conjugating enzyme 1"
FT                   /id="PRO_0000391959"
FT   ACT_SITE        116
FT                   /note="Glycyl thioester intermediate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   168 AA;  19238 MW;  6254DFBA19B97115 CRC64;
     MVDEATKRTL AAIPLLKTRA GPRDKDQWVG RLKEELVSLI KYVENNKKQD NDWFRLESNK
     EGTRWFGKCW YVHNLLKYEF DVEFDIPVTY PGTAPEIALP ELDGKTAKMY RGGKICLTDH
     FKPLWARNVP KFGIAHAMAL GLGPWLAVEI PDLVEKGIIV HKEKTSSE