ID   UFM1_BRUMA              Reviewed;          90 AA.
AC   A8Q8M5;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Ubiquitin-fold modifier 1;
DE   Flags: Precursor;
GN   ORFNames=Bm1_46275;
OS   Brugia malayi (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=6279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17885136; DOI=10.1126/science.1145406;
RA   Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA   Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA   Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA   Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA   Pop M., White O., Barton G.J., Carlow C.K.S., Crawford M.J., Daub J.,
RA   Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA   Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.-W.,
RA   Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA   McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA   Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA   Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA   Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA   Blaxter M.L., Scott A.L.;
RT   "Draft genome of the filarial nematode parasite Brugia malayi.";
RL   Science 317:1756-1760(2007).
CC   -!- FUNCTION: Ubiquitin-like modifier protein which binds to a number of as
CC       yet unidentified target proteins. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UFM1 family. {ECO:0000305}.
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DR   EMBL; DS239419; EDP30472.1; -; Genomic_DNA.
DR   RefSeq; XP_001900717.1; XM_001900682.1.
DR   AlphaFoldDB; A8Q8M5; -.
DR   SMR; A8Q8M5; -.
DR   STRING; 6279.A8Q8M5; -.
DR   GeneID; 6104137; -.
DR   KEGG; bmy:BM_BM7521; -.
DR   CTD; 6104137; -.
DR   WormBase; Bm7521b; BM39646; WBGene00227782; Bma-ufm-1.
DR   HOGENOM; CLU_175114_0_0_1; -.
DR   InParanoid; A8Q8M5; -.
DR   OMA; INPAQNA; -.
DR   OrthoDB; 1575050at2759; -.
DR   Proteomes; UP000006672; Unassembled WGS sequence.
DR   GO; GO:0071569; P:protein ufmylation; IEA:InterPro.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   InterPro; IPR005375; UFM1.
DR   PANTHER; PTHR15825; PTHR15825; 1.
DR   Pfam; PF03671; Ufm1; 1.
DR   PIRSF; PIRSF038027; Ubiquitin-like_Ufm1; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
PE   3: Inferred from homology;
KW   Isopeptide bond; Reference proteome; Ubl conjugation pathway.
FT   CHAIN           1..87
FT                   /note="Ubiquitin-fold modifier 1"
FT                   /id="PRO_0000392013"
FT   PROPEP          88..90
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000392014"
FT   CROSSLNK        87
FT                   /note="Glycyl lysine isopeptide (Gly-Lys) (interchain with
FT                   K-? in acceptor proteins)"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   90 AA;  9715 MW;  467716E8C1706923 CRC64;
     MEHAVGKVTF KITLTSDPKL PFKVLSVPES TPFTAVLKFA AEEFKVPAAT SAIITNDGVG
     INPTQSAGNI FLKHGSELRL IPRDRVGYCE