UGAL1_ARATH
ID UGAL1_ARATH Reviewed; 336 AA.
AC Q9C521;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=UDP-galactose transporter 1 {ECO:0000303|PubMed:15456736};
DE Short=At-UDP-GalT1 {ECO:0000303|PubMed:15456736};
GN Name=UDP-GALT1 {ECO:0000312|EMBL:CAG18176.1};
GN OrderedLocusNames=At1g77610 {ECO:0000312|Araport:AT1G77610};
GN ORFNames=T5M16.20 {ECO:0000312|EMBL:AAG51677.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION.
RC STRAIN=cv. Columbia; TISSUE=Silique;
RX PubMed=15456736; DOI=10.1093/glycob/cwh159;
RA Bakker H., Routier F., Oelmann S., Jordi W., Lommen A., Gerardy-Schahn R.,
RA Bosch D.;
RT "Molecular cloning of two Arabidopsis UDP-galactose transporters by
RT complementation of a deficient Chinese hamster ovary cell line.";
RL Glycobiology 15:193-201(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=25053812; DOI=10.1073/pnas.1406073111;
RA Rautengarten C., Ebert B., Moreno I., Temple H., Herter T., Link B.,
RA Donas-Cofre D., Moreno A., Saez-Aguayo S., Blanco F., Mortimer J.C.,
RA Schultink A., Reiter W.D., Dupree P., Pauly M., Heazlewood J.L.,
RA Scheller H.V., Orellana A.;
RT "The Golgi localized bifunctional UDP-rhamnose/UDP-galactose transporter
RT family of Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:11563-11568(2014).
CC -!- FUNCTION: Nucleotide sugar transporter that specifically transports
CC UDP-galactose. {ECO:0000269|PubMed:15456736}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TPT transporter family. TPT (TC 2.A.7.9)
CC subfamily. {ECO:0000305}.
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DR EMBL; AJ633720; CAG18176.1; -; mRNA.
DR EMBL; AC010704; AAG51677.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36000.1; -; Genomic_DNA.
DR EMBL; AF360161; AAK25871.1; -; mRNA.
DR EMBL; AY113887; AAM44935.1; -; mRNA.
DR PIR; F96805; F96805.
DR RefSeq; NP_565158.1; NM_106409.4.
DR AlphaFoldDB; Q9C521; -.
DR SMR; Q9C521; -.
DR BioGRID; 29315; 1.
DR IntAct; Q9C521; 1.
DR STRING; 3702.AT1G77610.1; -.
DR iPTMnet; Q9C521; -.
DR PaxDb; Q9C521; -.
DR PRIDE; Q9C521; -.
DR ProteomicsDB; 233032; -.
DR EnsemblPlants; AT1G77610.1; AT1G77610.1; AT1G77610.
DR GeneID; 844096; -.
DR Gramene; AT1G77610.1; AT1G77610.1; AT1G77610.
DR KEGG; ath:AT1G77610; -.
DR Araport; AT1G77610; -.
DR TAIR; locus:2204690; AT1G77610.
DR eggNOG; KOG1441; Eukaryota.
DR HOGENOM; CLU_022332_2_2_1; -.
DR InParanoid; Q9C521; -.
DR OMA; LQYVEVT; -.
DR OrthoDB; 938634at2759; -.
DR PhylomeDB; Q9C521; -.
DR PRO; PR:Q9C521; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C521; baseline and differential.
DR Genevisible; Q9C521; AT.
DR GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IBA:GO_Central.
DR GO; GO:0005457; F:GDP-fucose transmembrane transporter activity; IDA:UniProtKB.
DR GO; GO:0005459; F:UDP-galactose transmembrane transporter activity; IDA:UniProtKB.
DR GO; GO:0005460; F:UDP-glucose transmembrane transporter activity; IDA:UniProtKB.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:0015783; P:GDP-fucose transmembrane transport; IDA:UniProtKB.
DR GO; GO:0072334; P:UDP-galactose transmembrane transport; IDA:UniProtKB.
DR GO; GO:0015786; P:UDP-glucose transmembrane transport; IDA:UniProtKB.
DR InterPro; IPR004853; Sugar_P_trans_dom.
DR Pfam; PF03151; TPT; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Sugar transport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..336
FT /note="UDP-galactose transporter 1"
FT /id="PRO_0000406119"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 83..103
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 278..298
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 336 AA; 37791 MW; 947C3ABD89E6F544 CRC64;
MEEGSMFRSL LAILQWWGFN VTVIIMNKWI FQKLDFKFPL SVSCVHFICS SIGAYIVIKV
LKLKPLIVVD PEDRWRRIFP MSFVFCINIV LGNVSLRYIP VSFMQTIKSF TPATTVVLQW
LVWRKYFDWR IWASLVPIVG GILLTSVTEL SFNMFGFCAA LFGCLATSTK TILAESLLHG
YKFDSINTVY YMAPFATMIL GIPALLLEGS GILSWFEAHP APWSALIIIL SSGVLAFCLN
FSIFYVIHST TAVTFNVAGN LKVAVAVMVS WLIFRNPISY MNAVGCGITL VGCTFYGYVR
HMLSQQTPGT PRTPRTPRSK MELLPLVNND KLEGKV
